Cochrane Database of Systematic Reviews 2003
DOI: 10.1002/14651858.cd000032
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Energy and protein intake in pregnancy

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Cited by 291 publications
(231 citation statements)
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References 79 publications
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“…Our findings are supported by a Cochrane review that concluded that less energy intake during pregnancy is strongly associated with poor fetal growth, and underweight during pregnancy can also be possibly associated with the risk of preterm birth [14]. On the other hand, meta-analysis of five trials on balanced protein energy supplementation during pregnancy showed no difference between the incidence of term and preterm birth [15].…”
Section: Discussionsupporting
confidence: 81%
“…Our findings are supported by a Cochrane review that concluded that less energy intake during pregnancy is strongly associated with poor fetal growth, and underweight during pregnancy can also be possibly associated with the risk of preterm birth [14]. On the other hand, meta-analysis of five trials on balanced protein energy supplementation during pregnancy showed no difference between the incidence of term and preterm birth [15].…”
Section: Discussionsupporting
confidence: 81%
“…27 Kramer et al, in their systematic review of 16 RCTs and quasi experimental studies on balanced energy protein supplementation to pregnant women reported reduction in incidence of SGA (RR 0.66, 95% CI 0.49-0.89), stillbirths (RR 0.62, 95% CI 0.40-0.98) and improved birth weight (Mean difference of 73g, 95% CI 30-117). 28 Cochrane systematic review of 21 RCTs on multiple micronutrient supplementation to pregnant women in comparison with two or fewer micronutrients resulted in a significant effect on low birth weight (RR 0.88, 95% CI 0.85-0.91), SGA (RR 0.89, 95% CI 0.83-0.96) and preterm birth (RR 0.97, 95% CI 0.94-0.99). 29 Significant past medical history was found in 52% of the IUGR group in comparison to 8% in control group, 24% of foetal growth retardation cases had history of infertility.…”
Section: Discussionmentioning
confidence: 99%
“…However, under conditions of chronic undernutrition, supplementation of energy, proteins as well as micronutrients to the level of recommended dietary allowance during pregnancy resulted in only marginal improvements in birth weight (Christian et al, 2003;Kramer and Kakuma, 2003). The limited efficacy of these supplements may be owing to the inability of the body to lay down lean mass during pregnancy, because pregnancy is too short a window to increase lean mass.…”
Section: Discussionmentioning
confidence: 99%