In today’s globalized world, need for competitiveness on one side and constant pressure on the reduction of negative environmental impacts on the other side, are forcing industrial companies to systematically analyse all possibilities for the optimization of their production processes. This paper presents a systematic approach for improving energy efficiency in industrial facilities. Special attention was given to activities that were necessary for the proper identification of energy saving potential and implementation of selected energy efficiency measures in the complex industrial environment. The proposed approach includes four main activities: (1) energy auditing, identification and valorisation of opportunities for improving energy efficiency, (2) identification of key personnel who needs to be trained and motivated to become involved and to make energy efficient decisions in practice, (3) implementation of selected energy efficiency measures and (4) continuous monitoring and verification of achieved results. The proposed approach has been tested in the real industrial environment and the results are confirming that significant energy savings and overall improvement of competitiveness can be reached. Additionally, special emphasis was placed on soft elements like cooperation between energy experts, process operators and maintenance staff that are crucial for the overall success.