Energy expenditure and body composition in patients with anorexia nervosa

Vaisman, Nachum; Rossi, M; Goldberg, Eudice; Dibden, Lionel J.; Wykes, Linda; Pencharz, Paul B.

doi:10.1016/s0022-3476(88)80032-5

Cited by 77 publications

(41 citation statements)

References 16 publications

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“…As seen in patients with anorexia nervosa, they may adapt metabolically to a situation of suboptimal intestinal absorption with downregulation of their BMR (21)(22)(23)(24)(25). BMR was calculated with the use of equations that may not apply in a patient population that is subjected to semistarvation and adaptation for a time (8).…”

mentioning

confidence: 99%

The use of metabolic balance studies in the objective discrimination between intestinal insufficiency and intestinal failure

Prahm

Brandt

Askov-Hansen

et al. 2017

The American Journal of Clinical Nutrition

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, which were equivalent to findings in research settings (differences of 3.6% and 8.7%; P = 0.65 and 0.60, respectively). Oral failure defined as energy intake ,130% of calculated BMR or WW intake ,40 g $ kg body weight -1 $ d -1 was seen in 71% and 82% of the 10% of patients with the lowest energy absorption and WW absorption, respectively. Conclusions: In clinical settings, the borderlines between INS and IF were not significantly different from those in research settings, even in an unselected patient population in which oral failure was also a predominant cause of nutritional dyshomeostasis. MBSs may be recommended to identify the individual patient in the spectrum from INS to IF, to objectivize the cause of nutritional dyshomeostasis (oral failure, malabsorption, or both), and to quantify the effects of treatment. Am J Clin Nutr 2017;106:831-8.

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mentioning

confidence: 99%

The use of metabolic balance studies in the objective discrimination between intestinal insufficiency and intestinal failure

Prahm

Brandt

Askov-Hansen

et al. 2017

The American Journal of Clinical Nutrition

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“…The REE has to be reduced in AN patients to preserve their energy sources and restrict their energy needs, and the assessment of REE is considered to be a useful tool for following the progress of AN during refeeding (Vaisman et al, 1988). A previous study showed that the empiric caloric prescription was significantly higher than the measured REE (Schebendach et al, 1995).…”

Section: Discussionmentioning

confidence: 99%

“…For these reasons, it is thought to be very important to evaluate the changes in REE after refeeding therapy in AN patients. Body size parameters such as BSA, hormones such as thyroid hormone, cytokines such as leptin, and food intake are all known to regulate REE (Pauly et al, 2000;Platte et al, 1994;Vaisman et al, 1988), but the exact correlations between REE and these factors have not been fully examined in AN patients, especially in those in adolescence. A recent study reported the longitudinal changes in REE and plasma leptin levels in AN patients and demonstrated that leptin was unlikely to be responsible for an increase in REE during 1 week of refeeding therapy (Pauly et al, 2000).…”

Section: Discussionmentioning

confidence: 99%

“…It has been reported that malnutrition is accompanied by physiological abnormalities such as reduced resting energy expenditure (REE) (Platte, Pirke, Trimborn, Pietsch, Krieg, & Fichter, 1994;Vaisman, Rossi, Goldberg, Dibden, Wykes, & Pencharz, 1988) or expansion of the volume of extracellular water (Shizgal, 1985). REE has been shown to be reduced in AN patients, and this reduction might represent a biological tendency to preserve energy sources and cut energy needs (Vaisman et al, 1988). REE is regulated not just by body size but also by other factors such as food intake and hormones (Halliday, Hesp, Stalley, Warwick, Altman, & Garrow, 1979).…”

Section: Introductionmentioning

confidence: 99%

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Resting energy expenditure and plasma leptin levels in adolescent girls with anorexia nervosa

Satoh

Shimizu

Lee

et al. 2003

Intl J Eating Disorders

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Objective: Our aim was to examine the relationship between resting energy expenditure (REE) and circulating leptin levels during long-term refeeding in adolescent girls with anorexia nervosa (AN). Method: We measured REE, the plasma leptin level, the free T 3 level, body surface area (BSA), and dietary energy intake in AN adolescents before and 8 weeks after refeeding therapy. Results: All parameters in AN subjects before the refeeding therapy were significantly lower than those in AN subjects after the therapy and in the controls. There were no significant differences in REE and BSA between posttherapy AN subjects and controls, but plasma leptin levels in the posttherapy AN subjects were still significantly lower than those in the controls. Significant correlations between REE and BSA were detected in the AN subjects both before and after the refeeding therapy, but REE did not correlate significantly with plasma leptin level in either of the AN groups. Discussion: Our results suggest that the REE in AN subjects after long-term refeeding therapy is not associated with the changes in plasma leptin levels but with BSA.

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“…Low REEs had been observed previously in under nourished subjects [ 18. 20, 22] and in anorec tic patients [4,19,21]. This is mostly due to the extreme reduction in the body size of these chronically underfed individuals [4.…”

Section: Discussionmentioning

confidence: 99%

Postprandial Thermogenesis in Leanness and Anorexia Nervosa

Scalfi¹,

Coltorti²,

Borrelli³

et al. 1992

Ann Nutr Metab

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Resting energy expenditure (REE) and postprandial thermogenesis (PPT) after the ingestion of a mixed test meal (3.56 MJ, 850 kcal) were determined in 7 anorectic patients, 7 very lean women and 8 control women. REE is absolute value was sharply decreased in the anorectics, but did not significantly differ between the very lean and the control subjects. On the other hand, when adjusted for body weight, REE only tended (p = 0.18) to be lower in the anorectics in comparison to the control women. PPT was similar in the anorectics (187.2 ± 24.6 kJ/4 h) and the controls (200.7 ± 16.8kJ/4h), but lower in the lean subjects (137.5 ± 20.0 kJ/4h: p < 0.05) than in the other two groups. The present study shows that the thermic response to the ingestion of a mixed test meal was not decreased in undernourished anorectic patients whereas it was significantly reduced in very lean healthy women.

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Energy expenditure and body composition in patients with anorexia nervosa

Cited by 77 publications

References 16 publications

The use of metabolic balance studies in the objective discrimination between intestinal insufficiency and intestinal failure

The use of metabolic balance studies in the objective discrimination between intestinal insufficiency and intestinal failure

Resting energy expenditure and plasma leptin levels in adolescent girls with anorexia nervosa

Postprandial Thermogenesis in Leanness and Anorexia Nervosa

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