Phys. Chem. Chem. Phys.
 2024
DOI: 10.1039/d4cp02131b
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Energy gap of conformational transition related with temperature for the NACore of α-synuclein

Pengxuan Xia,
Yuanming Cao,
Qingjie Zhao
et al.

Abstract: Pathological aggregation of α-synuclein (α-syn) into amyloid fibrils is a major feature of Parkinson's disease (PD). The self-assembly of α-syn is mainly governed by Non-Amyloid-β Component core (NACore). However, the...

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