This research work presents an Ultra-Low-Power (ULP) Hybrid Micro Energy Harvester (HMEH) for biomedical application. This architecture uses the inputs of Thermoelectric Generator (TEG) and body vibration. TEG is based on temperature gradient between the ambient environment and human body. While vibration is based on the vibrate sources like motor that is able to generate an AC voltage. Having two sources overcome the issue of limitation caused by single source harvester but will result in impedance mismatching among the desired sources. The proposed of HMEH architecture consists of a control manager with Asynchronous Finite State Machine (AFSM) to grab the proper input value, a rectification to convert vibration input from AC to DC, a start-up to initialize the desired input, a Maximum Power Point Tracking (MPPT) to achieve maximum power extraction, a boost converter to boost up the input voltage, energy storage to keep the energy and voltage regulator to fix or produce the desired output voltage. A single power management circuit is used to reduce the number of components used and power losses. The HMEH will be modeled, designed and simulated using PSPICE software and then implement in 0.13 µm CMOS technology. Next, the developed HMEH will be coding using Verilog Hardware Description Language (VHDL) under mentor graphics and then download to Field Programmable Gate Array (FPGA) for real time implementation. The expectation from this ULP HMEH is to achieve 2.0-4.0 V of regulated voltage output from input sources range of 80-600 mV at start-up with an efficiency of 93%.