Energy loss for evaluating heart valve performance

Akins, Cary W.; Travis, Brandon R.; Yoganathan, Ajit P.

doi:10.1016/j.jtcvs.2007.12.059

Cited by 102 publications

(108 citation statements)

References 27 publications

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“…The more spread results with a higher range of mean errors of the EOA measurements in lower cardiac output (Fig. 7) is mainly due to inefficiency of the Gorlin's formula in calculating EOA for very large or very small valves (Akins et al, 2008). The fundamental function of a heart valve is to facilitate the unidirectional blood flow while maximising flow rate and minimising flow resistance.…”

Section: Discussionmentioning

confidence: 98%

Manufacturing and hydrodynamic assessment of a novel aortic valve made of a new nanocomposite polymer

Rahmani

Tzamtzis

Ghanbari

et al. 2012

Journal of Biomechanics

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Section: Discussionmentioning

confidence: 98%

Manufacturing and hydrodynamic assessment of a novel aortic valve made of a new nanocomposite polymer

Rahmani

Tzamtzis

Ghanbari

et al. 2012

Journal of Biomechanics

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“…1,11,12 Considering the branch PA control volume shown in Fig. 1a, the rate of total energy transferred to the blood pool at the MPA can be expressed as…”

Section: Total Energy At the Mpamentioning

confidence: 99%

Right Ventricular Inefficiency in Repaired Tetralogy of Fallot: Proof of Concept for Energy Calculations From Cardiac MRI Data

2010

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Repaired tetralogy of Fallot (rTOF) patients develop right ventricular (RV) dilatation and dysfunction. To prevent their demise, pulmonary valve replacement is necessary, though appropriate timing for it is challenged by a paucity of reliable diagnostic parameters. In this pilot study, we hypothesized that stroke work (SW) and energy calculations would delineate the inefficiency of RV performance in rTOF. RV SW was calculated for both an rTOF and a normal subject by utilizing RV pressure and volume measurements obtained during cardiac catheterization and MRI studies. Energy transfer rate and ratio were computed at the main pulmonary artery (PA). Compared to the normal RV, the rTOF RV had higher operating pressure, lower computed SW (0.078 J vs. 0.115 J for normal), and higher negative energy transfer at the PA (0.044 J vs. 0.002 J for normal). Furthermore, the energy transfer ratio was nearly twice as high for the normal RV (1.06) as for the rTOF RV (0.56). RV SW and energy transfer ratio delineate important operational efficiency differences in blood flow from the RV to the PA between rTOF and normal subjects. Our pilot data suggest that the rTOF RV is significantly less efficient than normal.

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“…This coefficient is not (yet) applied routinely, but more investigations are still being performed [30]. Additional analytical work has been performed and validated using experiments for the assessment of stenosis severity in unsteady flows [6,11].…”

Section: D Models For Assessing Asmentioning

confidence: 99%

Towards computational modelling of aortic stenosis

Loon

2009

Numer Methods Biomed Eng

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SUMMARYIn this paper fluid-structure interaction models of bioprosthetic or native aortic valves are proposed for the assessment of aortic stenosis severity. The fictitious domain approach is applied for the blood-valve interaction and the valve and root geometry are defined such that geometrical changes can easily be made. Clinically relevant scenarios are demonstrated using the models by introducing variable stroke volumes, differently shaped valve and root, leaflet fusion or calcifications. Systolic behaviour of the valves is observed and the severity of the occlusions is evaluated using the following clinically relevant criteria: geometrical orifice area, trans-valvular pressure gradient, effective orifice area and Energy loss coefficient. Within this context, the benefits, shortcomings and potential of the presented three-dimensional models are identified and discussed.

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Energy loss for evaluating heart valve performance

Cited by 102 publications

References 27 publications

Manufacturing and hydrodynamic assessment of a novel aortic valve made of a new nanocomposite polymer

Manufacturing and hydrodynamic assessment of a novel aortic valve made of a new nanocomposite polymer

Right Ventricular Inefficiency in Repaired Tetralogy of Fallot: Proof of Concept for Energy Calculations From Cardiac MRI Data

Towards computational modelling of aortic stenosis

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