In most regions of southern China, condensation frequently occurs on building surfaces during the period from March to April. This phenomenon has been affecting people’s safety and structural properties. This article proposes an innovative anti-condensation floor system based on the reverse Carnot cycle. The evaporation side treats the air and reduces the moisture content, and the heat extracted from the condensation side is recovered by a heat exchanger and transferred to the floor through capillary mats. Simulation studies of the dynamic operation performance have been conducted through the TRNSYS 18 software. The results show that an innovative anti-condensation floor system can effectively keep the floor dry in Guilin. At the same time, regarding the indoor comfort level index, the PMV value is within ±0.5, and the energy consumption of the system is 42% less than that of the cooling dehumidification system. The system also performs well in representative cities where the air moisture content is less than 12 g/kg. This article also provides a reference for the feasibility of radiant floor systems in humid climate areas.