The particle size ratio (PSR) is an important parameter for binary granular materials, which may a ect the microstructure and macro behaviors of granular materials. However, the e ect of particle ratio on granular assemblies with di erent arrangements is still unclear. To explore and further clarify the e ect of PSR in di erent packing structures, three types of numerical samples with regular, layered, and random packing are designed. Numerical results show that PSR has signi cant e ects on binary granular samples with regular packing. The larger the PSR, the stronger the strength, the larger the modulus, and the smaller the angle between the shear band and the load direction. And a theoretical solution of the peak stress ratio vs. PSR is obtained for regular packing, and the results by DEM are in good agreement with the theoretical solution. Under layered packing, PSR has little e ect on peak stress ratio due to similar microstructure obtained with the changing of PSR. The modulus slightly increased with the increase of PSR. Under random packing with small grain content of 50%, PSR has little e ect in the range of 0.5-0.9, but in a larger range, larger PSR leads to greater modulus.