Enfermedad de Castleman, un diagnóstico diferencial que no se debe olvidar en los tumores de mediastino: Caso clínico

J, Enrique Bellolio; Tapia, O.; C, Ma José Iriarte

doi:10.4067/s0034-98872014000600013

Cited by 1 publication

(1 citation statement)

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“…Because it is a rare disease, a high degree of diagnostic suspicion is required and, because there are no specific clinical and radiographic data, the diagnosis is anatomopathological [5,7]. This requires a complete resection of the affected ganglion [8]. As it happened in our case.…”

Section: Discussionmentioning

confidence: 88%

Castleman’s Disease about a Case

Ap¹,

Cp²,

Crc³

et al. 2019

J Clin Lab Med

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Castleman's disease is a very rare lymphoproliferative disorder. There are two Clinical forms: the unicentric, which is usually benign, and the multicentric progressive course. There are three described histological patterns: hyali neovascular of unicentric presentation, of plasma cells of multicentric presentation and the mixed one. The aim of this paper is to present a clinical case of multicentric Castleman's disease of hyaline vascular histology very little described in the literature. The patient started with asthenia, anorexia, profuse nocturnal sweating, weight loss, generalized lymphadenopathy, splenomegaly and respiratory episodes. At physical examination: multiple cervical, axillary and bilateral inguinal adenopathies. The diagnosis was made with the histopathological study of the resected ganglion, the evolution after the treatment has been favorable. Because there are no specific clinical and radiographic features, a high degree of diagnostic suspicion and the experience of the pathologist are required to diagnose this rare disease.

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Section: Discussionmentioning

confidence: 88%