Enfermedad de Kawasaki en un hospital pediátrico en México

Rodríguez, Fernando García; Pineda, Ángel de Jesús Flores; Villarreal-Treviño, Ana Victoria; Encinas, Diego Rubén Salinas; Herrera, Paola Bernardett Lara; Velázquez, María del Rocío Maldonado; Espinosa, Sarbelio Moreno; Fuentes, Enrique Faugier

doi:10.1016/j.bmhimx.2016.01.002

Cited by 11 publications

(21 citation statements)

References 30 publications

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“…Of these, only the one that received glucocorticoids presented a positive Harada score. Furthermore, 50% of the patients in this series presented echocardiography alterations, percentage higher than the 32% reported by Sotelo-Cruz 2 , the 29.4% reported by García-Rodríguez et al 11 , and the 35% reported by Surjit et al 22 However, it was similar to the 54% reported by Gil-Veloz et al 3 Our results may have been influenced by the characteristics of the patients in our series since there is female predominance, the median age is 2.1 years (lower than that reported in other series), 2,3,20 and there is a high frequency of atypical manifestations.…”

Section: Discussioncontrasting

confidence: 54%

“…Regarding clinical behavior, all patients met the criteria to define complete KD, similar to that found in the most extensive series published in Mexico 2,6,11 . Similarly, all the patients presented atypical manifestations, a higher proportion than that reported in other series 2,3,6,9,20,21 .…”

Section: Discussionmentioning

confidence: 58%

“…In Japan, 218 cases have been reported for every 100,000 children under 5 years old 6 ; in the U.S., 20 cases per year per 100,000 children; and in some Latin American countries, 11 annual cases per 100,000 children under 5 years old. In Mexico, the actual incidence is not known since there is only a report of some series of cases of the disease 4,[7][8][9][10][11] .…”

Section: Introductionmentioning

confidence: 99%

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Risk factors related to cardiovascular complications in children diagnosed with Kawasaki disease in Northwestern Mexico

Flores-Montes¹,

Valle-Leal²,

Arreguin-Reyes³

et al. 2023

BMHIME

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Background: Kawasaki disease (KD) is an acute systemic vasculitis of small and medium vessels, which occurs primarily in children. Its clinical picture shows as a febrile syndrome combined with vasculitis that can cause coronary artery abnormalities in 25% of untreated patients. The objective of this study was to describe the clinical behavior and to identify risk factors for cardiovascular complications in pediatric patients with KD in the second level hospital in northwestern Mexico. Methods: Under a case series design, we studied pediatric patients with a diagnosis of KD. We measured clinical variables, laboratory values, and the presence of cardiac complications; the probability of risk was determined with an odds ratio (OR) and the association with the Chi-squared test. Results: A total of 12 patients were included in the study, in which the female gender predominated; the mean age of presentation of KD was 2 years. The clinical presentation was complete in 100% of the cases, and patients also presented atypical manifestations; 50% of the patients studied had cardiovascular complications, and the most common was the coronary disease (33%). The variables male gender, age under 2 years, and anemia reported OR of 5.5-10 for suffering cardiovascular complications. Conclusions: Cardiovascular complications of KD are frequent (> 30%). Male gender, age under 2 years, and anemia increase the risk of cardiovascular complications.

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Section: Discussioncontrasting

confidence: 54%

Section: Discussionmentioning

confidence: 58%

Section: Introductionmentioning

confidence: 99%

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Risk factors related to cardiovascular complications in children diagnosed with Kawasaki disease in Northwestern Mexico

Flores-Montes¹,

Valle-Leal²,

Arreguin-Reyes³

et al. 2023

BMHIME

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“…Epidemiologic studies are rare in most European countries, and the incidence of KD has been reported as less than 17.6 per 100,000 less than 5-year-olds [20], remaining stationary without significant increases or decreases as in North America [4,21,22]. In Latin America, no systematic epidemiological study of KD has been performed in each country, although the incidence of KD has been reported sporadically in several countries [23,24]. The recently founded Latin American Kawasaki Disease Network (REKAMLATINA) is expected to improve the understanding of KD epidemiology in Latin America.…”

Section: Global Incidence Of Kdmentioning

confidence: 99%

Reality of Kawasaki disease epidemiology

Kim

2019

Korean J Pediatr

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Epidemiologic studies of Kawasaki disease (KD) have shown a new pattern or change of its occurrence suggestive of its pathophysiology or risk factors from the first patient with KD reported in 1961. The incidence of KD in Northeast Asian countries including Japan, South Korea, China, and Taiwan is 10–30 times higher than that in the United States and Europe. Knowing the true epidemiology of KD in each country and the availability of publications of KD epidemiology also could benefit general health care providers and general population. This would enable the early detection and treatment of KD, ultimately reducing the incidence of coronary artery complications and mortality. Therefore, efforts to investigate the true epidemiology of KD should be continued in every country using a questionnaire survey, National Health Insurance system data, or combined methods depending on each country’s medical environment to ensure high-quality care of patients with KD.

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“…La falta de estudios de esta enfermedad en Latinoamérica y Panamá limita el conocimiento que se tiene de ella y el comportamiento en nuestra población. Los resultados de este estudio arrojan que la EK en Panamá se comporta de forma similar en varios aspectos a lo ya reportado en otras latitudes, como la edad promedio de 29 meses, la que es similar a lo reportado en poblaciones latinoamericanas 6 . También se evidenció una frecuencia 2,6 veces mayor en pacientes bajo 3 años de edad y en forma similar con lo encontrado en otros países, se observó un predominio del sexo masculino independientemente de la edad 6,7 .…”

Section: Discussionunclassified

Estudio multicéntrico retrospectivo de los aspectos epidemiológicos, clínicos y terapéuticos de la enfermedad de Kawasaki en niños de Panamá

Estripeaut

Levy

Luciani

et al. 2020

Rev. chil. infectol.

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Antecedentes: La enfermedad de Kawasaki (EK) representa la principal causa de cardiopatía pediátrica adquirida en muchos países; sin embargo, hay pocos estudios publicados en Latinoamérica. Objetivo: Describir la epidemiología, los aspectos clínicos y el tratamiento de EK en niños en Panamá como parte del estudio de vigilancia de REKAMLATINA-2 en Latinoamérica. Pacientes y Métodos: Estudio retrospectivo, descriptivo, de pacientes internados con diagnóstico de EK, atendidos en tres hospitales pediátricos de Panamá del 1-enero-2009 al 31-diciembre-2013. Resultados: Se analizaron 111 pacientes, 61(54,9%) eran hombres. Todos fueron hospitalizados, siendo la media de hospitalización de 5,8 (4-7) días. La mediana de edad al ingreso fue de 28,9 (12-38) meses. Un 63,9% recibió antimicrobianos recientemente por otros posibles diagnósticos. Recibieron inmunoglobulina intravenosa (IGIV) 105 (94,6%) pacientes; de éstos, 10 (9,5%) fueron resistentes. Un 11,7% tuvo alteraciones cardiovasculares en el ECO inicial, de las cuales las lesiones coronarias se detectaron en 3 (2,9%) pacientes. Conclusiones: Los datos sugieren que EK en Panamá tiene una incidencia cercana a 2,05 x 100,000 bajo 15 años de edad y una frecuencia 2,6 veces mayor bajo 3 años de edad. Se observó un alto porcentaje de uso de antimicrobianos ambulatoriamente antes de la confirmación diagnóstica, lo cual sugiere reconocimiento tardío de EK en Panamá.

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Enfermedad de Kawasaki en un hospital pediátrico en México

Abstract: There were no important differences between classic and incomplete presentations. The incidence of cardiac alterations is less than previously reported in Mexico, but similar to that of other countries.

Cited by 11 publications

References 30 publications

Risk factors related to cardiovascular complications in children diagnosed with Kawasaki disease in Northwestern Mexico

Risk factors related to cardiovascular complications in children diagnosed with Kawasaki disease in Northwestern Mexico

Reality of Kawasaki disease epidemiology

Estudio multicéntrico retrospectivo de los aspectos epidemiológicos, clínicos y terapéuticos de la enfermedad de Kawasaki en niños de Panamá

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