Enfermedad de Wilson: experiencia pediátrica en Costa Rica

Risk of coronary artery involvement in Kawasaki disease

“…In our series, CRP and albumin levels have been related to the risk of developing CAD, as observed in other studies. 12 In our study, albuminemia has shown an AUC of 0.938, indicating that there is an excellent correlation among the lower albumin values (cut-off point <3.5 mg/dL) and CAD risk. Other previously described risk factors for the development of CAD, like age under 1 year old or older than 9 years old, leukocytosis or hyponatremia were not confirmed in our study, probably because of the sample size limitation.…”

Wilson disease in Costa Rica: Pediatric phenotype and genotype characterization

“…A total of 34 pediatric patients, from 28 families, were confirmed to have WD by a score ≥ 4 points in the Leipzig scoring system. From the 34 diagnosed patients, 23 were new and 11 had been previously reported . Previously reported patients had prior clinical diagnosis and were later confirmed molecularly (Table ).…”

“…From the 34 diagnosed patients, 23 were new and 11 had been previously reported. 18,19 Previously reported patients had prior clinical diagnosis and were later confirmed molecularly (Table 1). There were 15 female and 19 male patients diagnosed with no significant age difference between sexes (females = 7.9 ± 4.5 years, males = 9.4 ± 2.6 years, Welch ANOVA P = .2654).…”

Riesgo de afectación coronaria en la enfermedad de Kawasaki

“…12 En el nuestro, la albuminemia ha mostrado un AUC de 0,938, lo que indica que existe una excelente correlación entre los menores valores de albúmina (punto de corte <3,5 mg/dl) y el riesgo de AC. Otros factores de riesgo previamente descritos para el desarrollo de AC, como la edad menor de un año o mayor de 9 años, la leucocitosis o la hiponatremia, no se confirmaron en nuestro estudio, probablemente debido a la limitación que supone el tamaño muestral.…”