Enfermedad ósea de Paget

Eslava, Antonio Torrijos

doi:10.4321/s1889-836x2014000400001

Cited by 2 publications

(4 citation statements)

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“…Los osteoclastos multinucleados y las inclusiones citoplasmáticas o intranucleares son más típicos de la fase resortiva inicial. Además, cursa con fibrosis de médula ósea y shunts arterio-venosos [3][4][5] . Figura 3.…”

Section: Discussionunclassified

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Úbeda¹,

Monleón²,

Álvarez³

2023

Rev Osteoporos Metab Miner

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El cáncer de próstata es la lesión maligna no cutánea más frecuente en varones mayores de 70 años. El diagnóstico en estadíos avanzados de la enfermedad no es excepcional, mediante las lesiones metastásicas como debut. Las más características son óseas con comportamiento osteoblástico, infrecuentes en huesos maxilares. Por otro lado, la enfermedad ósea de Paget es una patología metabólica crónica por disfunción de osteoclastos. A nivel craneofacial la afectación característica es un aumento de tamaño, patrón en "copos de algodón" u osteoporosis circunscrita, siendo excepcional la localización única mandibular. Se presenta un caso de enfermedad ósea de Paget en hemimandíbula derecha sobre la que se desarrolla una metástasis por adenocarcinoma prostático.Palabras clave: enfermedad ósea de Paget, osteitis deformante, cáncer de próstata, metástasis, neoplasias orales. Metastatic prostate adeno-carcinoma and Paget's bone disease of the mandible SummaryProstate cancer is the most common non-cutaneous malignant lesion in males over 70 years of age. Diagnosis in advanced stages of the disease is not exceptional, through metastatic lesions as debut. The most characteristic of these lesions are osseous with osteoblastic behavior, uncommon in maxillary bones. On the other hand, Paget's disease is a chronic metabolic disorder attributed to osteoclast dysfunction. At the craniofacial level, the characteristic affectation is an increase in size, a "cotton flakes" pattern or circumscribed osteoporosis. The fact that this is only located in the mandible is exceptional. A case of Paget's disease of the right hemi-mandible bone is presented in which a metastasis is developed due to prostatic adenocarcinoma.

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Section: Discussionunclassified

“…Existe susceptibilidad genética, predomina en la raza caucásica, es discretamente más frecuente en varones y excepcional en menores de 40 años. No se dispone de tratamiento curativo, aunque se suelen prescribir bifosfonatos en función de la actividad metabólica y la sintomatología [2][3][4][5] .…”

Section: Introductionunclassified

Saber tibia

Úbeda¹,

Monleón²,

Álvarez³

2023

Rev Osteoporos Metab Miner

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“…Multinucleated osteoclasts and cytoplasmic or intranuclear inclusions are more typical of the initial rest phase. In addition, it presents with bone marrow fibrosis and arteriovenous shunts [3][4][5] .…”

Section: Discussionmentioning

confidence: 99%

“…It presents genetic susceptibility, is more predominant in Caucasians, slightly more frequent in males and exceptional in individuals under 40 years. No cure has been found, although bisphosphonates are usually prescribed depending on metabolic activity and symptomatology [2][3][4][5] .…”

Section: Introductionmentioning

confidence: 99%

Adenocarcinoma de próstata metastásico y enfermedad ósea de Paget mandibular

Prol

Ruiz-Oslé

Malaxetxebarria

et al. 2018

Rev Osteoporos Metab Miner

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Prostate cancer is the most common non-cutaneous malignant lesion in males over 70 years of age. Diagnosis in advanced stages of the disease is not exceptional, through metastatic lesions as debut. The most characteristic of these lesions are osseous with osteoblastic behavior, uncommon in maxillary bones. On the other hand, Paget's disease is a chronic metabolic disorder attributed to osteoclast dysfunction. At the craniofacial level, the characteristic affectation is an increase in size, a "cotton flakes" pattern or circumscribed osteoporosis. The fact that this is only located in the mandible is exceptional. A case of Paget's disease of the right hemi-mandible bone is presented in which a metastasis is developed due to prostatic adenocarcinoma.

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Enfermedad ósea de Paget

Cited by 2 publications

References 18 publications

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Adenocarcinoma de próstata metastásico y enfermedad ósea de Paget mandibular

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