While there is a voluminous scholarship focused on the nexus between resource extraction and development, the issue of how the harms and benefits of extraction are differentiated among several stakeholders based on factors such as their access to power, authority over decision-making, social status, and gender require further examination. This paper combines theoretical insights from assemblage thinking and political ecology to unpack the intertwined range of actors, networks, and structures of power that inform the differentiated benefits and harms of hydrocarbon extraction in Ghana. It can be observed from this study that power serves as a crucial ingredient in understanding relations among social groups, including purported beneficiaries of extractive activities, and other actors that constitute the networked hydrocarbon industry. Scale also reveals the relational nature of the different levels (i.e. global, national, sub-national, local) at which the socio-ecological ‘goods’ and ‘bads’ of hydrocarbon extraction become manifest. Based on these findings, the paper contributes to ongoing scholarly and policy discussions around extractivism by showing how a multi-scalar analysis reveals a more complex picture of the distributional politics, power asymmetry, and injustice that underpin resource extraction.