2024
DOI: 10.3390/biology13040221
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Engineering a Microphysiological Model for Regenerative Endodontic Studies

Diana Sanz-Serrano,
Montse Mercade,
Francesc Ventura
et al.

Abstract: Dental pulp infections are common buccal diseases. When this happens, endodontic treatments are needed to disinfect and prepare the root canal for subsequent procedures. However, the lack of suitable in vitro models representing the anatomy of an immature root canal hinders research on regenerative events crucial in endodontics, such as regenerative procedures. This study aimed to develop a 3D microphysiological system (MPS) to mimic an immature root canal and assess the cytotoxicity of various irrigating solu… Show more

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