Engineering ferrite nanoparticles with enhanced magnetic response for advanced biomedical applications

Wang, Y.; Miao, Yuqing; Li, G.; Su, Miaoda; Chen, X.; Zhang, H.; Zhang, Y.; Wei, Jiao; He, Yuan; Yi, Jie; Liu, Xiaoli; Fan, Haiming

doi:10.1016/j.mtadv.2020.100119

Cited by 42 publications

(28 citation statements)

References 111 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…No particular trend of I is, however, evident with the increase in the dopant amount. Often, in the literature, spinel inversion has been related to the reduction of particle sizes [ 5 , 6 ]; however, this is not the case, as almost all the synthesized materials were nanometric. Therefore, we can suppose that the presence of Ag as segregated phase caused oxygen vacancies in the spinel structure to balance the vacancies on iron sites introduced by the Ag segregation.…”

Section: Resultsmentioning

confidence: 99%

“…In recent years, biomedical applications of nanostructured biomaterials have increased remarkably [ 1 , 2 , 3 , 4 ]. In this regard, a very fascinating class of materials are undoubtedly the spinel ferrites, with main applications in contrast enhancement of magnetic resonance imaging (MRI), bio-magnetic separation, treatment of cancer by hyperthermia, and drug delivery and release [ 5 , 6 , 7 ]. Their advantages are numerous: improvement of pharmacokinetic and pharmacodynamics profiles of drugs, increased drug stability and solubility in aqueous phase, enhancement of accumulation in specific tissues through passive and active magnetic targeting and reduction of the drug concentration in non-targeted normal tissues and toxic side effects [ 7 ].…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Silver Doped Magnesium Ferrite Nanoparticles: Physico-Chemical Characterization and Antibacterial Activity

et al. 2021

View full text Add to dashboard Cite

Spinel phases, with unique and outstanding physical properties, are attracting a great deal of interest in many fields. In particular, MgFe2O4, a partially inverted spinel phase, could find applications in medicine thanks to the remarkable antibacterial properties attributed to the generation of reactive oxygen species. In this paper, undoped and Ag-doped MgFe2-xAgxO4 (x = 0.1 and 0.3) nanoparticles were prepared using microwave-assisted combustion and sol–gel methods. X-ray powder diffraction, with Rietveld structural refinements combined with micro-Raman spectroscopy, allowed to determine sample purity and the inversion degree of the spinel, passing from about 0.4 to 0.7 when Ag was introduced as dopant. The results are discussed in view of the antibacterial activity towards Escherichia coli and Staphylococcus aureus, representative strains of Gram-negative and Gram-positive bacteria. The sol–gel particles were more efficient towards the chosen bacteria, possibly thanks to the nanometric sizes of metallic silver, which were well distributed in the powders and in the spinel phase, with respect to microwave ones, that, however, acquired antibacterial activity after thermal treatment, probably due to the nucleation of hematite, itself displaying well-known antibacterial properties and which could synergistically act with silver and spinel.

show abstract

Section: Resultsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Silver Doped Magnesium Ferrite Nanoparticles: Physico-Chemical Characterization and Antibacterial Activity

et al. 2021

View full text Add to dashboard Cite

show abstract

“…One approach to increasing drug selectivity is by using nanoscale delivery systems, such as liposomes and polymeric nanoparticles, which possess cell-specific surface ligands. Several recent reviews have highlighted the common challenges that are faced by these non-magnetic biological and chemical targeting strategies [ 26 , 27 , 28 , 29 , 30 , 31 , 32 , 33 , 34 , 35 , 36 ]. Of these challenges, the most intractable is the body’s own physiological response to these foreign nanoscale systems, which quickly removes, metabolizes, and/or excretes them.…”

Section: Treatmentmentioning

confidence: 99%

“…Therefore, without proper surface engineering, the use of SPION in magnetothermal applications like tumor treatment could be limited [ 62 ]. More recently, these challenges are being met in a variety of ways, and several recent review papers cover these advances with respect to magnetothermal heating [ 28 , 32 , 34 , 36 ]. The responsiveness of magnetic particles to smaller AMFs can be optimized by altering their composition and shape to increase their magnetic susceptibility [ 28 ].…”

Section: Treatmentmentioning

confidence: 99%

Magnetic Nanoparticles in Biology and Medicine: Past, Present, and Future Trends

et al. 2021

View full text Add to dashboard Cite

The use of magnetism in medicine has changed dramatically since its first application by the ancient Greeks in 624 BC. Now, by leveraging magnetic nanoparticles, investigators have developed a range of modern applications that use external magnetic fields to manipulate biological systems. Drug delivery systems that incorporate these particles can target therapeutics to specific tissues without the need for biological or chemical cues. Once precisely located within an organism, magnetic nanoparticles can be heated by oscillating magnetic fields, which results in localized inductive heating that can be used for thermal ablation or more subtle cellular manipulation. Biological imaging can also be improved using magnetic nanoparticles as contrast agents; several types of iron oxide nanoparticles are US Food and Drug Administration (FDA)-approved for use in magnetic resonance imaging (MRI) as contrast agents that can improve image resolution and information content. New imaging modalities, such as magnetic particle imaging (MPI), directly detect magnetic nanoparticles within organisms, allowing for background-free imaging of magnetic particle transport and collection. “Lab-on-a-chip” technology benefits from the increased control that magnetic nanoparticles provide over separation, leading to improved cellular separation. Magnetic separation is also becoming important in next-generation immunoassays, in which particles are used to both increase sensitivity and enable multiple analyte detection. More recently, the ability to manipulate material motion with external fields has been applied in magnetically actuated soft robotics that are designed for biomedical interventions. In this review article, the origins of these various areas are introduced, followed by a discussion of current clinical applications, as well as emerging trends in the study and application of these materials.

show abstract

“…Devido ao pequeno tamanho dos nanomateriais e sua alta energia de superfície esses nanomateriais tendem a formar aglomerados ou agregados ou ainda adsorverem moléculas em sua superfície para alcançar uma situação de maior estabilidade, este fato torna a funcionalização ou adsorção de íons mais fácil e permite modificar esses materiais para uma grande gama de aplicações utilizando íons e moléculas que poderão fornecer as características desejadas (LIU et al, 2020;WANG et al, 2020 A adsorção específica dos ânions sobre as nanopartículas foi avaliada utilizado a medidas de potencial zeta em função do pH. Após uma alíquota desse material foi seca em estufa a 50 °C por 48 horas, o material foi macerado e peneirado a caracterização da amostra por difração de raios X (XRD).…”

Section: Introductionunclassified

ANÁLISE BROMATOLÓGICA DO ÓLEO DE COCO (Cocos nucifera L.) E DO ÓLEO DE ABACATE (Persea americana Mill.)

Rocha¹,

Uchôa²,

Rocha³

et al. 2021

A Geração De Novos Conhecimentos Na Química 2

View full text Add to dashboard Cite

Direitos para esta edição cedidos à Atena Editora pelos autores. Todo o conteúdo deste livro está licenciado sob uma Licença de Atribuição Creative Commons. Atribuição-Não-Comercial-NãoDerivativos 4.0 Internacional (CC BY-NC-ND 4.0).O conteúdo dos artigos e seus dados em sua forma, correção e confiabilidade são de responsabilidade exclusiva dos autores, inclusive não representam necessariamente a posição oficial da Atena Editora. Permitido o download da obra e o compartilhamento desde que sejam atribuídos créditos aos autores, mas sem a possibilidade de alterá-la de nenhuma forma ou utilizá-la para fins comerciais. Todos os manuscritos foram previamente submetidos à avaliação cega pelos pares, membros do Conselho Editorial desta Editora, tendo sido aprovados para a publicação com base em critérios de neutralidade e imparcialidade acadêmica.A Atena Editora é comprometida em garantir a integridade editorial em todas as etapas do processo de publicação, evitando plágio, dados ou resultados fraudulentos e impedindo que interesses financeiros comprometam os padrões éticos da publicação. Situações suspeitas de má conduta científica serão investigadas sob o mais alto padrão de rigor acadêmico e ético.

show abstract

Engineering ferrite nanoparticles with enhanced magnetic response for advanced biomedical applications

Cited by 42 publications

References 111 publications

Silver Doped Magnesium Ferrite Nanoparticles: Physico-Chemical Characterization and Antibacterial Activity

Silver Doped Magnesium Ferrite Nanoparticles: Physico-Chemical Characterization and Antibacterial Activity

Magnetic Nanoparticles in Biology and Medicine: Past, Present, and Future Trends

ANÁLISE BROMATOLÓGICA DO ÓLEO DE COCO (Cocos nucifera L.) E DO ÓLEO DE ABACATE (Persea americana Mill.)

Contact Info

Product

Resources

About