2017
DOI: 10.1007/s11705-017-1628-0
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Engineering of β-carotene hydroxylase and ketolase for astaxanthin overproduction in Saccharomyces cerevisiae

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Cited by 51 publications
(52 citation statements)
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“…According to the previous studies in our lab, combination of crtZ from Agrobacterium aurantiacum (Aa crtZ) and crtW from Brevundimonas vesicularis DC263(B. DC263 crtW) has a positive impact on the astaxanthin pathway in yeast [19,20]. Thus, AacrtZ and B. DC263crtW were chosen to construct the initial astaxanthin-producing strain.…”
Section: Construction Of Astaxanthin Producing Strainmentioning
confidence: 99%
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“…According to the previous studies in our lab, combination of crtZ from Agrobacterium aurantiacum (Aa crtZ) and crtW from Brevundimonas vesicularis DC263(B. DC263 crtW) has a positive impact on the astaxanthin pathway in yeast [19,20]. Thus, AacrtZ and B. DC263crtW were chosen to construct the initial astaxanthin-producing strain.…”
Section: Construction Of Astaxanthin Producing Strainmentioning
confidence: 99%
“…Modifying microbial cells to improve the production of the desired endogenous or exogenous metabolites is a broad aim at many areas of academic, industrial biotechnology and biosciences [8][9][10][11]. In recent years, the heterologous biosynthesis of astaxanthin has been successfully achieved in Escherichia coli [12][13][14][15][16][17], Saccharomyces cerevisiae [5,[18][19][20],Yarrowia lipolytic [21], and…”
Section: Introductionmentioning
confidence: 99%
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“…Here we would like to mention six Chinese groups from which you could get a common sense of the main research group on Synbio in China. They are Prof. Yang's group of Shanghai Institutes for Biological Sciences [20], Prof. Zhou's group of Jiangnan University [21], Prof. Xiao's group of Tianjin University [22], Prof. Su's group of Beijing University of Chemical Technology [23], Prof. Dai's group of Tsinghua University before 2018 (now of Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences [24]) and Prof. Yu's group of Zhejiang University [25].…”
Section: Bio-and Medical Are the New Trendsmentioning
confidence: 99%
“…Modifying cells to improve the production of the desired metabolite is a broad aim for many areas of academic and industrial biotechnology and biosciences [8][9][10][11]. In recent years, the heterologous yield of astaxanthin has been successfully achieved in Escherichia coli [12][13][14][15][16][17], Saccharomyces cerevisiae [5,[18][19][20], Oleaginous Yeast Yarrowia lipolytica [21], and Corynebacterium glutamicum [22] by introducing the biosynthesis pathway of astaxanthin. However, astaxanthin yield in microorganisms still not high enough for commercialization.…”
Section: Introductionmentioning
confidence: 99%