Engineering the Interface of Ceria and Silver Janus Nanoparticles for Enhanced Catalytic Performance in 4-Nitrophenol Conversion

Pallares, Roger M.; Karstens, Sarah L.; Arino, Trevor; Minor, Andrew M.; Abergel, Rebecca J.

doi:10.1021/acsanm.3c01394

Cited by 5 publications

(2 citation statements)

References 34 publications

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“…The gold concentration in the samples was measured using an inductively coupled plasma mass spectrometer Agilent 8900 (Agilent). Nanoparticles were acid-digested prior to mass spectrometry analysis. − …”

Section: Methodsmentioning

confidence: 99%

Improving Lyophilization and Long-Term Stability of Gold Nanostars for Photothermal Applications

Xi,

Zhang,

Thoröe-Boveleth

et al. 2023

ACS Appl. Nano Mater.

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Gold nanostars (AuNS) are anisotropic metal nanoparticles that display morphology-dependent optical properties. These include strong extinction coefficients in the nearinfrared region of the spectrum and near-field enhancements. AuNS have been widely used for biomedical applications, including sensing, imaging, and photothermal therapy. To promote the use of AuNS for commercial (pre)clinical purposes, the stability and shelf life need to be maximized. In pharmaceutics, lyophilization (also known as freeze-drying) is commonly employed to extend shelf life and facilitate logistics. However, lyophilization tends to induce stress on nanoparticles, causing irreversible aggregation. In this work, we studied the use of sucrose, glucose, sorbitol, poly(vinylpyrrolidone) (PVP), and poly(ethylene glycol) (PEG) as cryoprotectants during AuNS lyophilization, as well as their effect on particle shelf life, photothermal properties, and contrast agent performance. We explored three different AuNS that were obtained via one-pot synthesis with biocompatible 4-(2-hydroxyethyl)-1piperazinepropanesulfonic acid (EPPS), 4-(2-hydroxyethyl) piperazine-1-ethanesulfonic acid (HEPES), and 3-(N-morpholino) propanesulfonic acid (MOPS) as the seedless synthetic protocol did not require cytotoxic surfactants that may complicate biological applications. As a reference, we used citrate-coated spherical gold nanoparticles (AuNPs). While AuNS synthesized with EPPS and HEPES could be lyophilized and resuspended in water in the absence of a cryoprotectant, the use of cryoprotectants (particularly sucrose) facilitated their reconstitution and improved shelf life. AuNPs and AuNS synthesized with MOPS irreversibly aggregated during lyophilization and required PVP for resuspension and long-term storage. The use of selected cryoprotectants preserved the photothermal characteristics and photoacoustic imaging signal generation of the nanoparticles after freeze-drying. Taken together, these findings provide insights into improving the stability and shelf life of nanoparticles, potentially contributing to the development of AuNS as biomedical products.

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Section: Methodsmentioning

confidence: 99%

Improving Lyophilization and Long-Term Stability of Gold Nanostars for Photothermal Applications

Xi,

Zhang,

Thoröe-Boveleth

et al. 2023

ACS Appl. Nano Mater.

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“…In the last couple of decades, metal nanoparticles have been extensively used to catalyze a wide range of reactions, such as alcohol oxidations, carbon monoxide oxidation, carbon–carbon coupling reactions, borohydride reductions, and selective hydrogenations. ,− Nanoparticle size and shape strongly affect their catalytic performance. For example, size usually determines the induction time and reaction rate of nanocatalysts .…”

Section: Manipulating Chemistry Through Surface Curvaturementioning

confidence: 99%

Role of Surface Curvature in Gold Nanostar Properties and Applications

Zhang

Kießling

et al. 2023

ACS Biomater. Sci. Eng.

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Gold nanostars (AuNSs) are nanoparticles with intricate three-dimensional structures and shape-dependent optoelectronic properties. For example, AuNSs uniquely display three distinct surface curvatures, i.e. neutral, positive, and negative, which provide different environments to adsorbed ligands. Hence, these curvatures are used to introduce different surface chemistries in nanoparticles. This review summarizes and discusses the role of surface curvature in AuNS properties and its impact on biomedical and chemical applications, including surface-enhanced Raman spectroscopy, contrast agent performance, and catalysis. We examine the main synthetic approaches to generate AuNSs, control their morphology, and discuss their benefits and drawbacks. We also describe the optical characteristics of AuNSs and discuss how these depend on nanoparticle morphology. Finally, we analyze how AuNS surface curvature endows them with properties distinctly different from those of other nanoparticles, such as strong electromagnetic fields at the tips and increased hydrophilic environments at the indentations, together making AuNSs uniquely useful for biosensing, imaging, and local chemical manipulation.

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