2023
DOI: 10.1002/smll.202306451
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Engineering the Physical Microenvironment into Neural Organoids for Neurogenesis and Neurodevelopment

Minghui Li,
Heng Sun,
Zongkun Hou
et al.

Abstract: Understanding the signals from the physical microenvironment is critical for deciphering the processes of neurogenesis and neurodevelopment. The discovery of how surrounding physical signals shape human developing neurons is hindered by the bottleneck of conventional cell culture and animal models. Notwithstanding neural organoids provide a promising platform for recapitulating human neurogenesis and neurodevelopment, building neuronal physical microenvironment that accurately mimics the native neurophysical f… Show more

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