2023
DOI: 10.1063/5.0142537
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Engineering tools for quantifying and manipulating forces in epithelia

Liam P. Dow,
Toshi Parmar,
M. Cristina Marchetti
et al.

Abstract: The integrity of epithelia is maintained within dynamic mechanical environments during tissue development and homeostasis. Understanding how epithelial cells mechanosignal and respond collectively or individually is critical to providing insight into developmental and (patho)physiological processes. Yet, inferring or mimicking mechanical forces and downstream mechanical signaling as they occur in epithelia presents unique challenges. A variety of in vitro approaches have been used to dissect the role of mechan… Show more

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