The Sub-Saharan African-born community in Australia is significantly underrepresented in health research, partly, due to challenges associated with collecting their primary data. Based on experience from a mixed-method study comprising 24 in-depth interviews and a survey of 253 participants in the community, this communication paper highlights a number of ‘high-level’ practical issues that might be encountered when collecting primary data from the community and provides suggestions for future studies. Included in this paper is a brief discussion of important lessons from the fieldwork that are critical for achieving successful data collection from the community. The lessons include difficulty of proving external validity for samples drawn from the community, difficulty of developing a reliable sampling frame, challenges in selecting appropriate support organisations, risk of low response to surveys and language barrier. The study concludes that understanding the ethnic diversities in this community and engaging appropriate support organisations are critical to achieving a successful data collection experience.