The interaction of intense femtosecond laser pulses with solid targets is a topic that has attracted a large amount of interest in science and applications. For many of the related experiments a large energy deposition or absorption as well as an efficient coupling to extreme ultraviolet (XUV), X-ray photon generation, and/or high energy particles is important. Here, much progress has been made in laser development and in experimental schemes, etc. However, regarding the improvement of the target itself, namely its geometry and surface, only limited improvements have been reported. The present paper investigates the formation of laser-induced periodic surface structures (LIPSS or ripples) on polished thick copper targets by femtosecond Ti:sapphire laser pulses. In particular, the dependence of the ripple period and ripple height has been investigated for different fluences and as a function of the number of laser shots on the same surface position. The experimental results and the formation of ripple mechanisms on metal surfaces in vacuum by femtosecond laser pulses have been analysed and the parameters of the experimentally observed “gratings” interpreted on base of theoretical models. The results have been specifically related to improve high-intensity femtosecond-laser matter interaction experiments with the goal of an enhanced particle emission (photons and high energy electrons and protons, respectively). In those experiments the presently investigated nanostructures could be generated easily in situ by multiple pre-pulses irradiated prior to a subsequent much more intense main laser pulse.