Enhanced anti-<i>Escherichia coli</i>properties of Fe-doping in MgO nanoparticles

Hong, Xiaoyu; Yang, Yan; Li, Xiaohua; Abitonze, Maurice; Diko, Catherine Sekyerebea; Zhao, Jiao; Ma, Qiao; Liu, Weifeng; Zhu, Yimin

doi:10.1039/d0ra09590g

Cited by 8 publications

(2 citation statements)

References 43 publications

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“…In both the MgO/Cu and MgO/Ag groups, a substantial increase in the fluorescence intensity was observed in the first 10 min (Figures b and S2). It was indicated that the composite NPs were in direct and complete contact with the aqueous solution, catalyzing the adsorbed oxygen or oxygen in the water to generate ROS rapidly, , which further reacted with DCFH to produce DCF. As time progressed, the fluorescence intensity increased slowly due to the depletion of oxygen in the water.…”

Section: Resultsmentioning

confidence: 99%

Nanofibrous Dressing with Nanocomposite Monoporous Microspheres for Chemodynamic Antibacterial Therapy and Wound Healing

Xu,

Cai,

Gao

et al. 2023

ACS Omega

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The excessive use of antibiotics and consequent bacterial resistance have emerged as crucial public safety challenges for humanity. As a promising antibacterial treatment, using reactive oxygen species (ROS) can effectively address this problem and has the advantages of being highly efficient and having low toxicity. Herein, electrospinning and electrospraying were employed to fabricate magnesium oxide (MgO)based nanoparticle composited polycaprolactone (PCL) nanofibrous dressings for the chemodynamic treatment of bacteria-infected wounds. By utilizing electrospraying, erythrocyte-like monoporous PCL microspheres incorporating silver (Ag)-and copper (Cu)-doped MgO nanoparticles were generated, and the unique microsphere-filament structure enabled efficient anchoring on nanofibers. The composite dressings produced high levels of ROS, as confirmed by the 2,7dichloriflurescin fluorescent probe. The sustained generation of ROS resulted in efficient glutathione oxidation and a remarkable bacterial killing rate of approximately 99% against Staphylococcus aureus (S. aureus). These dressings were found to be effective at treating externally infected wounds. The unique properties of these composite nanofibrous dressings suggest great potential for their use in the medical treatment of bacteria-infected injuries.

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Section: Resultsmentioning

confidence: 99%

Nanofibrous Dressing with Nanocomposite Monoporous Microspheres for Chemodynamic Antibacterial Therapy and Wound Healing

Xu,

Cai,

Gao

et al. 2023

ACS Omega

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show abstract

“…strategy. [15][16][17][18][19][20] In addition, using the co-doping, sol-gol and synthesis of composites with heterojunction structure methods could improve the antibacterial property of metal oxides. [21][22][23] Through the reformation of MgO NPs, many of these reports relate their high antibacterial activity of MgO NPs to the increase of oxygen vacancies.…”

Section: Introductionmentioning

confidence: 99%

Enhanced antibacterial activity of acid treated MgO nanoparticles on Escherichia coli

Hong

Yang

et al. 2021

RSC Adv.

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Copper/ cerium metal organic frame work as highly efficient structures for solar power-induced hydrogen generation through the process of water splitting

El-Fawal,

El Naggar,

Morshedy

2024

Energy Conversion and Management

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Enhanced anti-Escherichia coliproperties of Fe-doping in MgO nanoparticles

Abstract: Fe was successfully incorporated into MgO nanoparticles (NPs), which has significant enhanced the antibacterial property of MgO NPs against E. coli.

Cited by 8 publications

References 43 publications

Nanofibrous Dressing with Nanocomposite Monoporous Microspheres for Chemodynamic Antibacterial Therapy and Wound Healing

Nanofibrous Dressing with Nanocomposite Monoporous Microspheres for Chemodynamic Antibacterial Therapy and Wound Healing

Enhanced antibacterial activity of acid treated MgO nanoparticles on Escherichia coli

Copper/ cerium metal organic frame work as highly efficient structures for solar power-induced hydrogen generation through the process of water splitting

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