Enhanced Antifungal Activity of Electrosprayed Poly (vinyl alcohol)/Chitosan Nanospheres Loaded with Sage Essential Oil on the Viability of <i>Aspergillus niger and Botrytis cinerea</i>

Erarslan, Azime; Karakaş, Canan Yağmur; Bozkurt, Fatih; Sağdıç, Osman

doi:10.1002/slct.202300296

Cited by 8 publications

(3 citation statements)

References 57 publications

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“…The tested MIC value against B. cinerea was 0.35 μL/mL, surpassing the efficacy of Angelica archangelica EO (5.5 g/L) and sage EO reported by previous studies. , The antifungal activity of Poliomintha longiflora EO against B. cinerea and C.…”

Section: Resultsmentioning

confidence: 52%

“…82 The tested MIC value against B. cinerea was 0.35 μL/mL, surpassing the efficacy of Angelica archangelica EO (5.5 g/L) and sage EO reported by previous studies. 83,84 The antifungal activity of Poliomintha longiflora EO against B. cinerea and C. gloeosporioides has been confirmed, with MIC values of 0.8 and 1.0 g/L, respectively. 85 The inhibition of MEO on C. gloeosporioides was slightly worse than on B. cinerea, represented by an MIC of 0.45 and an IC 50 of 0.3193 μL/ mL, yet it outperformed the savory EO, which had an IC 50 of 0.5842 μL/mL reported by Sarkhosh et al 86 The fungitoxic function of peppermint EO was confirmed in which this substance drastically hindered the growth of mycelia at 100 μL/mL.…”

Section: Extraction and Antioxidant Activity Assay Of Heomentioning

confidence: 86%

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A Novel Preservative Film with a Pleated Surface Structure and Dual Bioactivity Properties for Application in Strawberry Preservation due to Its Efficient Apoptosis of Pathogenic Fungal Cells

Zhang,

Bao

et al. 2024

J. Agric. Food Chem.

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Botrytis cinerea (B. cinerea) and Colletotrichum gloeosporioides (C. gloeosporioides) were isolated from the decaying strawberry tissue. The antifungal properties of Monarda didyma essential oil (MEO) and its nanoemulsion were confirmed, demonstrating complete inhibition of the pathogens at concentrations of 0.45 μL/mL (0.37 mg/mL) and 10 μL/mL, respectively. Thymol, a primary component of MEO, was determined as an antimicrobial agent with IC 50 values of 34.51 (B. cinerea) and 53.40 (C. gloeosporioides) μg/mL. Hippophae rhamnoides oil (HEO) was confirmed as a potent antioxidant, leading to the development of a thymol-HEO-chitosan film designed to act as an antistaling agent. The disease index and weight loss rate can be reduced by 90 and 60%, respectively, with nutrients also being well-preserved, offering an innovative approach to preservative development. Studies on the antifungal mechanism revealed that thymol could bind to FKS1 to disrupt the cell wall, causing the collapse of mitochondrial membrane potential and a burst of reactive oxygen species.

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Section: Resultsmentioning

confidence: 52%

Section: Extraction and Antioxidant Activity Assay Of Heomentioning

confidence: 86%

A Novel Preservative Film with a Pleated Surface Structure and Dual Bioactivity Properties for Application in Strawberry Preservation due to Its Efficient Apoptosis of Pathogenic Fungal Cells

Zhang,

Bao

et al. 2024

J. Agric. Food Chem.

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“…Stapf [64]; Hyssopus officinalis L. [65]; Pistacia atlantica Desf. [66]; Salvia officinalis L. [67]; Thymus daenensis Celak. and Anethum graveolens L. [68]; Thymus vulgaris L. and Piper betel L. [69]; Zataria multiflora Boiss.…”

Section: Comparison With Other Nanocarriers Tested Against the Same P...mentioning

confidence: 99%

Uncaria tomentosa-Loaded Chitosan Oligomers–Hydroxyapatite–Carbon Nitride Nanocarriers for Postharvest Fruit Protection

Santiago-Aliste,

Sánchez-Hernández,

Buzón-Durán

et al. 2023

Agronomy

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Given the risks associated with synthetic fungicides, it is crucial to explore safe and sustainable alternatives. One potential solution is using bioactive natural products (BNPs). However, BNPs face challenges like lability, solubility, and lack of specificity. These issues can be addressed through nanoencapsulation. This study focuses on the evaluation of novel chitosan oligomers–hydroxyapatite–carbon nitride (COS–HAp–g-C3N4) nanocarriers (NCs) for encapsulating BNPs, specifically an extract from Uncaria tomentosa bark. The NCs were characterized by transmission electron microscopy, energy-dispersive X-ray spectroscopy, and infrared spectroscopy. The NCs were monodisperse, with a mean diameter of 250 nm, and showed an encapsulation efficiency of 82%. The suitability of the loaded NCs (COS–HAp–g-C3N4–BNP, in a 2:1:0.5:1 weight ratio) for postharvest fruit protection was investigated in vitro and ex situ at a laboratory scale. Results regarding their efficacy against Botrytis cinerea on strawberries, Colletotrichum gloeosporioides on mangoes, Penicillium expansum on apples, Monilinia laxa on peaches, and Sclerotinia sclerotiorum on kiwifruit are presented. Minimum inhibitory concentrations of 250, 375, 375, 250, and 187.5 μg·mL−1 were found in vitro, respectively, while higher doses (500, 750, 750, 250, and 375 μg·mL−1, respectively) were needed to achieve effective control in postharvest tests on artificially inoculated fruit. These findings suggest that NCs containing extracts from U. tomentosa bark show promise as biorational agents and as alternatives to conventional fungicides for managing postharvest phytopathogens.

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Production and comprehensive characterization of PVA/chitosan transdermal composite mats loaded with bioactive curcumin; evaluation of its release kinetics, antioxidant, antimicrobial, and biocompatibility features

Ciftci,

Özarslan,

Evcimen Duygulu

2024

J of Applied Polymer Sci

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Recently, researchers have shown increasing interest in incorporating bioactive substances with therapeutic properties into fiber‐structured mat biomaterials, which are favored as tissue scaffolds for wound healing applications. In this study, curcumin (Cur)‐loaded polyvinyl alcohol (PVA)/chitosan (CS) composite mats were produced using the electrospinning method and followed by the freeze‐drying method. Scanning electron microscope images proved the homogeneous structure of the composite mats, and Fourier transform infrared spectroscopy analysis showed that the Cur‐loaded composite mats were successfully produced. The antibacterial activity of Cur‐loaded PVA/CS composite mats was evaluated against Escherichia coli and Staphylococcus aureus, and the results showed that the antibacterial activity of the composite mats increased with the addition of Cur. Furthermore, the antioxidant test, release kinetics tests, and in vitro biocompatibility studies such as cytotoxicity, staining, and scratch assay of Cur‐loaded PVA/CS composite mats were carried out. The results showed that adding Cur enhanced the bioactivity of PVA10/CS10 composite mats. Further, the biocompatibility findings indicated that 10Cur‐PVA10/CS10 exhibited the highest viability value throughout all incubation periods compared with the other samples. Moreover, the highest rate of scratch closure on the 10Cur‐PVA/10/CS10 composite mats was observed at the end of 24 h compared with the other composite mats. These findings indicate that the Cur‐loaded PVA10/CS10 composite mats significantly positively impact cell migration and wound healing, making them a promising candidate as transdermal composite mats for tissue engineering and wound care applications.

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Enhanced Antifungal Activity of Electrosprayed Poly (vinyl alcohol)/Chitosan Nanospheres Loaded with Sage Essential Oil on the Viability of Aspergillus niger and Botrytis cinerea

Cited by 8 publications

References 57 publications

A Novel Preservative Film with a Pleated Surface Structure and Dual Bioactivity Properties for Application in Strawberry Preservation due to Its Efficient Apoptosis of Pathogenic Fungal Cells

A Novel Preservative Film with a Pleated Surface Structure and Dual Bioactivity Properties for Application in Strawberry Preservation due to Its Efficient Apoptosis of Pathogenic Fungal Cells

Uncaria tomentosa-Loaded Chitosan Oligomers–Hydroxyapatite–Carbon Nitride Nanocarriers for Postharvest Fruit Protection

Production and comprehensive characterization of PVA/chitosan transdermal composite mats loaded with bioactive curcumin; evaluation of its release kinetics, antioxidant, antimicrobial, and biocompatibility features

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