Enhanced Antimicrobial Cellulose/Chitosan/ZnO Biodegradable Composite Membrane

Abstract

In this study, chitosan and sugarcane cellulose were used as film-forming materials, while the inorganic agent zinc oxide (ZnO) and natural compound phenyllactic acid (PA) were used as the main bacteriostatic components to fabricate biodegradable antimicrobial composite membranes. The water absorption and antimicrobial properties were investigated by adjusting the concentration of PA. The scanning electron microscopy (SEM), Fourier transform infrared spectroscopy (FTIR) and X-ray diffraction (XRD) results demonstrated that the components of the composite membrane were successfully integrated. The addition of ZnO improved the mechanical and antimicrobial properties of the composite membrane, while the addition of PA with high crystallinity significantly reduced the water absorption and swelling. Moreover, the addition of 0.5% PA greatly improved the water absorption of the composite membrane. The results of antimicrobial experiments showed that PA improved the antimicrobial activity of the composite membrane against Staphylococcus aureus, Escherichia coli, Aspergillus niger and Penicillium rubens. Among them, 0.3% PA had the best antimicrobial effect against S. aureus, E. coli and A. niger, while 0.7% PA had the best antimicrobial effect against P. rubens.

Active chitosan- poly (vinyl alcohol) film reinforced with zinc oxide nanoparticles for food packaging applications

“…50 Different results were found by Sun et al, who fabricated of Cellulose/Chitosan/ZnO/PA composite membranes and demonstrated good antifungal activity against A. niger. 51…”

“…50 Different results were found by Sun et al, who fabricated of Cellulose/ Chitosan/ZnO/PA composite membranes and demonstrated good antifungal activity against A. niger. 51 On the other hand, Bailore et al demonstrated that the antifungal activity is affected by the formation of nanoclusters in the polymer matrix, they made pullulan/collagen blend film with dopant ZnO nanoparticles and tested the antifungal activity against A. niger, their films showed excellent antifungal activity with a zone 18 mm maximum inhibition for pullulan/collagen/ ZnONps (0.5%), they attribute this behavior to the fact that ZnONps affect the cellular functions of the fungus by increasing the nucleic acid content. The lowest concentration used in the test of nano ZnO (0.25%) was not effective enough, while the concentration of nano ZnO (1%) might have agglomerated and would have resulted in inefficient penetration into the fungal cells.…”

Synthesis and Characterization of 2-(Aminothiazole-4-yl) Coumarin-2-One, and Studying Its Nanoparticles as Antibacterial Activity

“…b. The nanoparticles carried on cellulose membrane [19]. The composite membrane was cut into discs with a diameter of 6 mm, and the antimicrobial activity was evaluated by measuring the inhibition zone surrounding each disc.…”

Preparation and Characterization of Chitosan/LDH Composite Membranes for Drug Delivery Application

“…Chitosan (CS) is a linear polysaccharide with N-acetyl-D-glucosamine and D-glucosamine units, used in biomedical applications, due to its remarkable properties, such as its hydrophilicity, biodegradability, biocompatibility, and low cost [ 13 , 14 , 15 , 16 ]. Chitosan is a polysaccharide derived from chitin [ 17 , 18 ].…”