Enhanced Binding Ability of β-Cyclodextrin Bearing Seven Hydrophobic Chains Each with a Hydrophilic End Group

Imamura, Kazuhisa; Ikeda, Hiroshi; Ueno, Akihiko

doi:10.1246/cl.2002.516

Cited by 6 publications

(4 citation statements)

References 2 publications

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“…11 The desired amphiphilic structures have been produced from ester linkage between all the C-6 of b-CD and the carboxyl group of N-acetylated resides: H 2 NeLeueCOOH, H 2 NeLeu-GlyeCOOH, H 2 NeLeu-Gly-LeueCOOH, and H 2 NeLeu-Gly-Leu-GlyeCOOH (Scheme 1).…”

Section: Resultsmentioning

confidence: 99%

Design and synthesis of a new series of amphiphilic peptide-β-cyclodextrins as phase transfer carriers for glucosamine

Seyedi¹,

Sadeghian²,

Jabbari³

et al. 2010

Tetrahedron

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Section: Resultsmentioning

confidence: 99%

Design and synthesis of a new series of amphiphilic peptide-β-cyclodextrins as phase transfer carriers for glucosamine

Seyedi¹,

Sadeghian²,

Jabbari³

et al. 2010

Tetrahedron

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“…Compound (10) which contain amphiphilic chains, was synthesized from per-amino--CD using peptide chemistry (Imamura et al, 2002) (Fig. 3).…”

Section: Alkylated Arylated and Lipid -Conjugated Cdsmentioning

confidence: 99%

Amphiphilic Cyclodextrins, Synthesis, Utilities and Application of Molecular Modeling in Their Design

Jabbari¹,

Sadeghian²

2012

Recent Advances in Novel Drug Carrier Systems

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“…Compound 7 (Scheme ), having amphiphilic chains, was prepared from per‐amino‐β‐CD using peptide chemistry 20…”

Section: Synthesis Of Amphiphilic Cyclodextrinsmentioning

confidence: 99%

Amphiphilic Cyclodextrins – Advances in Synthesis and Supramolecular Chemistry

2008

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Amphiphilic cyclodextrins represent a new generation of these oligosaccharides, which are well known previously as host molecules in water. Cyclodextrins are now being modified with polar groups, lipophilic groups and conjugates which elaborate further their amphiphilicity and molecular recognition. The resulting amphiphiles are host molecules capable of forming all the assemblies expected of amphiphiles, but showing additional supramolecular properties. Examples of these macrocyclic amphiphiles are by now known that form thermotropic liquid crystals, while lyotropic assemblies include micelles, unimolecular micelles, nanoparticles, monolayers and bilayer vesicles. The assembly proper- Cyclodextrin Amphiphiles: A New Generation of CyclodextrinsCyclodextrins (CDs) are macrocyclic oligosaccharides composed of -(+)-glucopyranosyl units linked α(1Ǟ4).[a] Centre for Synthesis and Chemical Biology of the UCD Con-

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Enhanced Binding Ability of β-Cyclodextrin Bearing Seven Hydrophobic Chains Each with a Hydrophilic End Group

Abstract: Seven adipic acid units each with a D-glucamine unit at the end were introduced to primary hydroxyl side of β-cyclodextrin to enlarge the hydrophobic cavity. The modification remarkably enhanced the binding ability for larger guests.

Cited by 6 publications

References 2 publications

Design and synthesis of a new series of amphiphilic peptide-β-cyclodextrins as phase transfer carriers for glucosamine

Design and synthesis of a new series of amphiphilic peptide-β-cyclodextrins as phase transfer carriers for glucosamine

Amphiphilic Cyclodextrins, Synthesis, Utilities and Application of Molecular Modeling in Their Design

Amphiphilic Cyclodextrins – Advances in Synthesis and Supramolecular Chemistry

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