Enhanced Biomolecule Concentration Sensing by Using Exceptional Points in a Microtube Cavity With Multiple Layers

Label-free optical biosensing: going beyond the limits

“…205 The authors theoretically showed that the sensitivity of this hybrid plasmon/vibrational system to RI variations can be maximized by selecting the thicknesses of plasmonic film and the numbers of graphene layers in the ribbons to tune the sytem to the generation of efficient EPs. Bin Liu et al 206 proposed a biosensing design based on a microtube cavity having multiple layers, in which the coupling of modes can be tailored to generate EPs by a careful selection of layer thicknesses. It was theoretically shown that the proposed biosensor design could provide the improvement of sensitivity up to 1000-fold compared to conventional methods.…”

WSe2 Negative Capacitance Field-Effect Transistor for Biosensing Applications

“…The increasing demand for early medical diagnostics and disease treatment underscores the importance of biosensors with high sensitivity, automation, integration, and continuous monitoring capabilities for detecting biological signals, 1 such as proteins, 2 nucleic acids, 3 enzymes, 4 and small biomolecules. 5 Various biosensors have been designed based on different sensing mechanisms. 6−10 Among these, field-effect transistor (FET) biosensors have garnered attention for their high sensitivity, rapid response, label-free operation, small size, specificity, low cost, and ease of on-chip integration.…”