Enhanced bone regeneration and formation around implants using guided bone regeneration

Abstract

This study investigated the use of a prototype expanded polytetrafluoroethylene membrane attached to bone with butyl-cyanoacrylate, in facilitating guided bone regeneration into bone defects and around titanium screws in rabbit femora. Two experimental models were used to assess bone growth. The first model investigated two unicortical defects in each femora. The second was bone growth in a 500-micron engineered space around one transcortical titanium screw. In the first model there was a significant increase in bone formation at 1 and 2 months in the membrane groups (p < 0.01) as compared to the controls. In the second model the percentage of bone in contact with the implant was significant at 1 and 2 months in the defects covered with membrane compared to the uncovered defects. The uncovered defects had fibrous tissue adherent to the implant continuous with the overlying soft tissue. Our study demonstrated three points: this membrane can be used to increase bone regeneration into defects, this technique allows bone to grow directly around an implant, and butyl-cyanoacrylate can be used in deep soft tissue and bone applications without any apparent deleterious effects.

Guided tissue regeneration with use of β‐TCP/chitosan composite membrane

“…In general, an effective barrier membrane should have appropriate mechanical strength to occlude the rapid growth of repairing tissues (epithelium and gingival connective tissue) away from the root surface and maintain a protective space over the defect that would allow migration of bone cells from the surrounding alveolar bone into the targeted area 9. Ideally, clinical manageability of the barrier membrane is also a necessary consideration during surgical procedures.…”

Guided Bone Regeneration Using Cyanoacrylate-Combined Calcium Phosphate in a Dehiscence Defect: A Histologic Study in Dogs

“…24,26 Other studies have described the application of cyanoacrylate in block bone grafts and GBR procedures. 22,27 Cyanoacrylate-combined calcium phosphate (CCP) is 1 of these substitutes; cyanoacrylate-based grafts can bind to and stabilize the biomaterials within the defect. 22,28 The purpose of this study was to evaluate the effects of CCP as a candidate barrier membrane substitute in GBR.…”

Avaliação da efetividade das membranas de colageno e celulose no tratamento de defeitos osseos tipo fenestração associados a implantes dentais

“…Antes da colocação dos implantes, foram confeccionados, com mna broca trefina 12 de 5mm de diâmetro, defeitos ósseos circulares na fuce mediai da tíbia, contidos no longo eixo dos implantes, com o objetivo de simular defeitos periimplantares do tipo fenestração (fig. 1 ).…”

“…Em seqüência, o implante foi removido de seu invólucro e inserido manualmente através de um dispositivo plástico, que permitiu o início da colocação sem o contato manual com o mesmo. Posteriormente, quando o implante já possuía alguma retenção no seu leito receptor, o dispositivo plástico era removido, e12 • Implantes -Biomateriais Dentoflex Instrumentos Cirúrgicos uma chave de catraca à cabeça do implante para completar sua colocação.…”