Enhanced Depth Imaging Optical Coherence Tomography of the Sclera in Dome-Shaped Macula

Imamura, Yutaka; Iida, Tomohiro; Maruko, Ichiro; Zweifel, Sandrine; Spaide, Richard F.

doi:10.1016/j.ajo.2010.08.014

Cited by 227 publications

(180 citation statements)

References 20 publications

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“…Imamura et al 41 reported that the mean subfoveal scleral thickness measured by EDI-OCT in 25 eyes with high myopia without dome-shaped macula was 281 mm. Maruko et al 42 reported that the mean subfoveal scleral thicknesses in 58 highly myopic eyes measured by highpenetration (HP) OCT was 335 mm.…”

Section: Discussionmentioning

confidence: 99%

Scleral thickness in highly myopic eyes measured by enhanced depth imaging optical coherence tomography

Hayashi

Ito

Takahashi

et al. 2013

Eye

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Purpose The purpose of this study was to determine the subfoveal scleral thickness in highly myopic eyes by enhanced depth imaging spectral-domain optical coherence tomography (EDI-OCT) and to identify the ocular parameters significantly associated with the scleral thickness. Methods The subfoveal scleral thickness of myopic eyes (Z À 8 diopters (D) or axial length Z26.5 mm) was examined by EDI-OCT. The correlations between the thickness and the best-corrected visual acuity (BCVA), refractive error, axial length (AL), the subfoveal retinal thickness, choroidal thickness, and posterior staphyloma height 2 mm from the fovea were investigated. Results A total of 75 eyes of 54 patients (21 men, 33 women; mean age, 62.3 ± 11.3 years; mean AL, 30.2 ± 1.68 mm) were studied. Eighteen eyes had no pathological retinochoroidal lesions, and 57 eyes had retinochoroidal lesion, that is, myopic schisis, choroidal neovascularization, and other retinochoroidal pathologies. The mean subfoveal scleral thickness was 284.0±70.4 lm, and the thickness was significantly correlated negatively with the absolute value of the nasal and overall average posterior staphyloma height (Po0.05 and Po0.01, respectively). The subfoveal scleral thickness was also significantly correlated negatively with the relative value of the superior, nasal, and overall average posterior staphyloma height (Po0.05, Po0.01, and Po0.001, respectively). Stepwise analyses showed that the factor most significantly associated with the scleral thickness was the average relative posterior staphyloma height (F ¼ 16.0, Po0.001). The scleral thickness was not significantly different between eyes with and without myopic retinochoroidal pathologies (P40.05). Conclusion Posterior staphyloma formation was a key factor associated with a posterior scleral thinning in highly myopic eyes.

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Section: Discussionmentioning

confidence: 99%

Scleral thickness in highly myopic eyes measured by enhanced depth imaging optical coherence tomography

Hayashi

Ito

Takahashi

et al. 2013

Eye

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“…6 Techniques such as enhanced-depth imaging (EDI) have been employed to provide better visualization of the choroid using standard clinical OCT machines. 2,[7][8][9][10][11] Portable spectral domain OCT (SD-OCT) imaging with an 840-nm to 100-nm bandwidth source (Bioptigen, Inc., Research Triangle Park, NC) has allowed clinicians to obtain SD-OCT images in subjects which were previously inaccessible. Using this device, clinicians have imaged preterm and term infants in the operating room, clinical exam visits, neonatal intensive care units, and newborn nursery, finding significant variation in retinal foveal morphology.…”

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confidence: 99%

Choroid Development and Feasibility of Choroidal Imaging in the Preterm and Term Infants Utilizing SD-OCT

Moreno

O’Connell

Chiu

et al. 2013

Invest. Ophthalmol. Vis. Sci.

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PURPOSE. To determine whether choroidal imaging is feasible in preterm and term infants using an 840-nm portable spectral domain optical coherence tomography (SD-OCT) system without the use of enhanced-depth imaging techniques and to assess choroidal development by comparing choroidal thickness of preterm infants, term infants, and adults.METHODS. SD-OCT images were obtained from 86 preterm infants, 59 term infants, and nine adults using a portable SD-OCT system plus nine adults using a tabletop system. An unprocessed image across the macula from one randomly selected eye of each participant was selected for determination of whether the choroidal-scleral junction (CSJ) could be visualized and for measurement of choroidal thickness.RESULTS. Subfoveal CSJ was visualized in 96% of young-preterm infants (imaged from 30-36 weeks postmenstrual age [PMA]); 78% of term-aged preterm infants (imaged from 37-42 weeks PMA); 49% of term infants; and 39% of adult subjects. Racial pigmentation did not affect CSJ visibility in young-preterm infants (P ¼ 0.57). Subfoveal choroidal thickness (SFCT) in young-preterm infants, term-aged preterm infants, term infants, and adults was 176 6 53 lm, 289 6 92 lm, 329 6 66 lm, and 258 6 66 lm, respectively, and these were all statistically significantly different from one another except term-aged preterms to adults.CONCLUSIONS. Infant choroid can be imaged with a portable SD-OCT system without enhanced depth imaging. Melanin in the RPE and choroid does not hinder outer choroidal imaging in young-preterm infants without advanced retinopathy of prematurity (ROP). In preterm infants, choroidal thickness increased with age but was thinner when compared to term infants suggesting delayed development due to ROP.

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“…Благодаря ОКТ высокого разрешения ста-ло возможным получать высокодифферен-цированные срезы сетчатки, в частности хо-риоидеи и склеры, с определением толщины каждого слоя [18]. Было замечено, что на не-которых глазах с очень высокой миопией с по-мощью EDI-OCT идентифицируются склера и даже передние орбитальные ткани.…”

Section: особенности диагностики и клинической картиныunclassified

“…Толщина склеры при КМ в проекции макулы составила около 570 ± 221 мкм, а у пациентов с миопией высокой степени без данной особенности тол-щина склеры была значительно меньше и соста-вила 281 ± 85 мкм. В то время как за предела-ми зоны 3000 мкм от центральной ямки такие отличия не выявлены в обеих группах [13,18]. Толщина хориоидеи на всём протяжении у паци-ентов с КМ без особенностей течения данного процесса (наличия ХНВ, субретинальной жид-кости) существенно не отличалась от пациентов с высокой миопией, а по некоторым данным, была даже тоньше принятых среднестатистиче-ских значений (у пациентов с миопией высокой степени без КМ) -146,5 ± 56 мкм [7].…”

Section: особенности диагностики и клинической картиныunclassified

Dome-shaped macula phenomenon

Melikhova¹,

Gatsu²

2018

Ophthalmology Reports

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This article provides a review of the literature of domestic and foreign studies on the newly described, insufficiently explored and poorly diagnosed pathology of the organ of vision - the dome-shaped macula (DSM). This pathology is an anatomical feature of the structure of the eye and is formed in most cases at medium and high myopia. For the first time, this condition was revealed in 2008 with the help of high resolution optical coherence tomography, and is characterized by local thickening of the sclera in the macular area with dome formation. Currently the final reason for DSM formation is not yet found. Studies are conducted to identify the mechanisms for the formation of this feature and to predict the variants of its course. Particular attention in the article is paid to the review of various changes in the retina and pigment epithelium in patients with dome-shaped macula. Methods and features of diagnosis of this condition, as well as differential diagnosis with choroidal hemangioma, which is very difficult, are also considered. The article presents an overview of current methods of treating this condition. Failures, as well as effective and promising methods of treating the neurosensory retinal detachment, occurring on the background of the dome-shaped macula, are described. Timely and correct diagnosis on the basis of characteristic clinical picture allows to avoid ineffective treatment, as well as to select the necessary set of diagnostic procedures for dynamic observation and identification of features of the disease. (For citation: Melikhova MV, Gatsu MV. Dome-shaped macula phenomenon. Ophthalmology Journal. 2018;11(1):71-77. doi: 10.17816/OV11171-77).

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Enhanced Depth Imaging Optical Coherence Tomography of the Sclera in Dome-Shaped Macula

Cited by 227 publications

References 20 publications

Scleral thickness in highly myopic eyes measured by enhanced depth imaging optical coherence tomography

Scleral thickness in highly myopic eyes measured by enhanced depth imaging optical coherence tomography

Choroid Development and Feasibility of Choroidal Imaging in the Preterm and Term Infants Utilizing SD-OCT

Dome-shaped macula phenomenon

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