“…220,221,224,225,[227][228][229][230][232][233][234][235][236][237][238][239][240][241][242][243][244][245][246][247]249,250,[253][254][255][256] For the 1 RCT, 218 no significant difference between control hospitals and intervention hospitals, both unadjusted (P=0.306; Diff, −0.208; 95% CI, −0.620 to 0.204) and adjusted (P=0.736; OR, 0.94; 95% CI, 0.79-1.13), was demonstrated. Of the 31 observational studies reporting on cardiac arrest rates, 1 before-after study using an aggregated weighted scoring system (Modified Early Warning Score [MEWS]) reported significantly higher cardiac arrest rates in MEWS bands 3 to 4 after intervention, but not in MEWS bands 0 to 2 or 5 to 15, and overall cardiac arrest rate significance was not reported 232 ; 7 studies with no adjustment demonstrated no significant improvement in cardiac arrest rates after the introduction of a MET system 224,225,[228][229][230]233,234 ; 15 studies with no adjustment demonstrated significant improvement in cardiac arrest rates after the introduction of a MET system 220,221,…”