Enhanced green mediated synthesis of optimized Ag-Cu bimetallic nanoparticles using Leucas aspera and its application in Anti-cancer activity against alveolar cancer

Yang, Hai‐Tao; Zhang, Xueyun; Velu, Periyannan; Liu, Xuejiao; Vijayalakshmi, Annamalai

doi:10.1016/j.matlet.2021.131645

Cited by 10 publications

(3 citation statements)

References 6 publications

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“…Confirmation of the crystalline nature of the TiO 2 NPs was achieved through XRD analysis, which involved measuring the 2θ angle from 10°to 80°. [48] The spectra exhibited the formation of anatase TiO 2 , as shown (Figure 4) by the presence of diffraction peaks (2θ) at angles 25.25°, 37.86°, 48.09°, 53.90°, 101) is associated with the anatase phase structure of TiO 2 NPs, as referenced by the JCPDS card number 01-015-0875 which is similar to the earlier findings. [42] Scherrer's formula was used to determine the average size of nanoparticles in terms of crystalline structure.…”

Section: Ftirsupporting

confidence: 86%

“…X‐ray diffraction (XRD) examination was conducted in order to ascertain the crystal phase and crystallite size of TiO 2 NPs. Confirmation of the crystalline nature of the TiO 2 NPs was achieved through XRD analysis, which involved measuring the 2θ angle from 10° to 80° [48] . The spectra exhibited the formation of anatase TiO 2 , as shown (Figure 4) by the presence of diffraction peaks (2θ) at angles 25.25°, 37.86°, 48.09°, 53.90°, 54.95°, 62.96°, 68.81°, 70.26° and 75.16°.…”

Section: Resultsmentioning

confidence: 99%

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Green Biosynthesis of TiO₂Nanoparticles Using Aqueous Extract ofBrassica juncea(L.) Czern Seed: Characterization, Antimicrobial, Antioxidant and Anticancer Activities

Jeyaraj,

Mary Saral

2024

ChemistrySelect

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Primary objective of this research was to examine the biogenic production of TiO2 NPs using Brassica juncea (L.) Czern seed and investigate the prospective uses of thus synthesized nanoparticles in the area of biomedicine. The synthesized TiO2 NPs were subjected to characterization using several analytical methods namely TEM, UV‐vis, XRD, FE‐SEM, FTIR and EDAX. The average particle size (TEM) is found to be 38 nm, exhibiting irregular shapes. The FT‐IR spectra indicated that the extract contains functional groups, such as polyphenolic, hydroxyl and carboxylic groups, which are likely responsible for formation of nanoparticles. The cytotoxicity studies of the synthesized TiO2 NPs against breast cancer cells (MCF‐7) and lung cells (A549) are shown to be dosage dependent. The inhibitory doses (IC50) were determined to be 43.98 μg/mL and 74.50 μg/mL on MCF‐7 and A549 cells, respectively. Green synthesized TiO2 NPs were assessed for antioxidant activity inhibition rate (DPPH 89.42 %). TiO2 NPs exhibited a maximal zone of inhibition of Staphylococcus aureus 23±0.20 mm against and 20±0.30 against Klebsiella pneumoniae at a concentration of 100 μg/mL, indicating strong antibacterial activity. The findings suggest Brassica juncea (L.) Czern seed encapsulated TiO2 NPs possesses excellent biological applications which can be explored for its application in pharmaceutical field.

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Section: Ftirsupporting

confidence: 86%

Section: Resultsmentioning

confidence: 99%

Green Biosynthesis of TiO₂Nanoparticles Using Aqueous Extract ofBrassica juncea(L.) Czern Seed: Characterization, Antimicrobial, Antioxidant and Anticancer Activities

Jeyaraj,

Mary Saral

2024

ChemistrySelect

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“…The highly magnetic properties of Au-Fe and Ni-Co bimetallic nanoparticles makes them suitable to use as contrast agent for CT and MRI diagnosis/prognosis imaging [224] and theranostic agent for tumors [225]. Similarly, Cu-Fe have been used for enhanced chemodynamic therapy [226], Pd-Pt, Au-Co, Au-Co, Ag-Cu, Au-Pt have been used for cancer therapeutics and anticancer activity [21,[227][228][229][230] and Au-Bi have been used for the inhibition of tumor cells [231]. In preventive medicine, the use of bimetallic nanoparticles is quite extensive and many of them are used as antimicrobial agents, antioxidants, antidiabetic, anti-Alzheimer, anti-inflammatory and drug delivery.…”

Section: Biological Applicationsmentioning

confidence: 99%

Synthesis of Bimetallic Nanoparticles and Applications—An Updated Review

Idris

Roy

2023

Crystals

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The manipulation of matter at the atomic level (nanotechnology) has experienced an explosion in research interest in recent years. Bimetallic nanoparticles are vital due to their high biocompatibility, stability and comparatively less toxicity. The synthesis methods that include physical, chemical and biological methods are explored and explained in detail, along with their advantages. They have a wide range of applications due to their synergistic properties including biological applications (in medicine and agriculture), environmental application (in water treatment and removal of toxic contaminants), engineering application (in nanosensors, nanochips and nano-semiconductors) and chemical and physical application (in optics, catalysis and paints). The green synthesis approach is a promising method of synthesis that can give rise to more biocompatible and less toxic bimetallic nanoparticles due to increasing environmental pollution. However, despite these interesting attributes of bimetallic nanoparticle, there is still much work to be done to improve the biocompatibility of bimetallic nanoparticles because of their toxicity and potentially hazardous effects.

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Biogenic Synthesis of Ag–CuO Nanoparticles and Its Antibacterial, Antioxidant, and Catalytic Activity

Idris,

Roy

2023

J Inorg Organomet Polym

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Enhanced green mediated synthesis of optimized Ag-Cu bimetallic nanoparticles using Leucas aspera and its application in Anti-cancer activity against alveolar cancer

Cited by 10 publications

References 6 publications

Green Biosynthesis of TiO₂Nanoparticles Using Aqueous Extract ofBrassica juncea(L.) Czern Seed: Characterization, Antimicrobial, Antioxidant and Anticancer Activities

Green Biosynthesis of TiO₂Nanoparticles Using Aqueous Extract ofBrassica juncea(L.) Czern Seed: Characterization, Antimicrobial, Antioxidant and Anticancer Activities

Synthesis of Bimetallic Nanoparticles and Applications—An Updated Review

Biogenic Synthesis of Ag–CuO Nanoparticles and Its Antibacterial, Antioxidant, and Catalytic Activity

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Enhanced green mediated synthesis of optimized Ag-Cu bimetallic nanoparticles using Leucas aspera and its application in Anti-cancer activity against alveolar cancer

Cited by 10 publications

References 6 publications

Green Biosynthesis of TiO2Nanoparticles Using Aqueous Extract ofBrassica juncea(L.) Czern Seed: Characterization, Antimicrobial, Antioxidant and Anticancer Activities

Green Biosynthesis of TiO2Nanoparticles Using Aqueous Extract ofBrassica juncea(L.) Czern Seed: Characterization, Antimicrobial, Antioxidant and Anticancer Activities

Synthesis of Bimetallic Nanoparticles and Applications—An Updated Review

Biogenic Synthesis of Ag–CuO Nanoparticles and Its Antibacterial, Antioxidant, and Catalytic Activity

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Product

Resources

About

Green Biosynthesis of TiO₂Nanoparticles Using Aqueous Extract ofBrassica juncea(L.) Czern Seed: Characterization, Antimicrobial, Antioxidant and Anticancer Activities

Green Biosynthesis of TiO₂Nanoparticles Using Aqueous Extract ofBrassica juncea(L.) Czern Seed: Characterization, Antimicrobial, Antioxidant and Anticancer Activities