Enhanced molecular imprinted electrochemical sensing of histamine based on signal reporting nanohybrid

Mahnashi, Mater H.; Mahmoud, Ashraf M.; Alhazzani, Khalid; Alanazi, Ahmed Z.; Algahtani, Mohammad; Alaseem, Ali; Alqahtani, Yahya S.; El-Wekil, Mohamed M.

doi:10.1016/j.microc.2021.106439

Cited by 43 publications

(10 citation statements)

References 41 publications

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“…Among these studies mentioned in Table 1 , the molecularly imprinted polymers (MIPs) are the most robust and stable, offering particular recognition properties that are suitable for on-site detection. The application of MIP offers a low detection limit, even though the detection limit of this study is higher than that of Mahnashi et al; 41 in terms of stability, this method is better. Furthermore, the application of lithium perchlorate to increase the conductivity of SPE modification is cheaper compared to gold.…”

Section: Resultscontrasting

confidence: 57%

Inspecting Histamine Isolated from Fish through a Highly Selective Molecularly Imprinted Electrochemical Sensor Approach

Munir¹,

Rahmawati

Jamal

et al. 2023

ACS Omega

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Numerous analytical approaches have been developed to determine histamine levels in food samples due to its health consequences. Consuming histamine over the Food and Drug Administration (FDA)-regulated 50 mg kg −1 limit would result in chronic toxicity. Consequently, the present study discusses a novel electrochemical approach to evaluate histamine levels in fish products via a molecularly imprinted polymer (MIP) on an electrode surface. The film was produced with electropolymerized polyurethane (PU), which maintained the histamine compound. Fourier-transform infrared (FTIR) spectroscopy was applied to verify the MIP manufactured in this study. The capability of the polymer was measured by assessing its electron shifts with cyclic voltammetry (CV) and electrochemical impedance spectroscopy (EIS). Differential pulse voltammetry (DPV) was also employed to validate the sensing method. The MIP/ screen-printed electrode (SPE) and non-imprinted polymer (NIP)/SPE recorded a linear response ranging from 1 to 1000 nmol L −1 at the 1.765 and 709 nmol L −1 detection limits. The sensing technique was subsequently utilized to determine the histamine levels in selected samples at room temperature (25 °C). Generally, the sensor allowed the accurate and precise detection of histamine in the fish samples. Furthermore, the approach could be categorized as a simple technique that is low-cost and suitable for on-site detections.

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Section: Resultscontrasting

confidence: 57%

Inspecting Histamine Isolated from Fish through a Highly Selective Molecularly Imprinted Electrochemical Sensor Approach

Munir¹,

Rahmawati

Jamal

et al. 2023

ACS Omega

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“…This may be explained by the effect of strong acidic and alkaline solutions, which decrease the affinity between PEDOT/Au-Ag (1 : 3) and target molecule HA. 2 As shown in Fig. 5e, CVs recorded on successive addition of HA from 100 nM to 1 mM showed a linear current response.…”

Section: Resultsmentioning

confidence: 64%

“…1 Histamine (2-(1Himidazol-4-yl)ethanamine) (HA) is one such vasoactive amine that acts as a mediator in both physiological and pathological processes. 2,3 In particular, it performs a dual role as a neurotransmitter and neuromodulator, regulating the release of other neurotransmitters. 4,5 An abnormal level of HA leads to several neurological disorders, such as schizophrenia, amyotrophic lateral sclerosis, scombroid poisoning, and several other lethal allergic symptoms.…”

Section: Introductionmentioning

confidence: 99%

“…4,5 An abnormal level of HA leads to several neurological disorders, such as schizophrenia, amyotrophic lateral sclerosis, scombroid poisoning, and several other lethal allergic symptoms. 2,[6][7][8] Various laborious and expensive techniques, such as fluorimetry, high-performance liquid chromatography, gas chromatography, enzyme immobilization, and antibody-based immunoassays, are employed to detect HA. 5,[9][10][11] While these techniques benchmark performance for HA detection, electroanalytical methods outperform them in terms of sensitivity, selectivity, amenable miniaturization, integration into wireless sensors, and remote sensing applications.…”

Section: Introductionmentioning

confidence: 99%

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In situ engineering of Au–Ag alloy embedded PEDOT nanohybrids at a solvent/non-solvent interface for the electrochemical enzyme-free detection of histamine

et al. 2023

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“…It was formed by the electro-polymerization of the functional monomer around the template. Specific binding sites are formed after the removal of the template, capable of identifying the analyte under study 17 – 20 . Interestingly, we found only one report in the literature describing the electrochemical sensing of Pseudomonas aeruginosa based on the fabrication of molecular imprinted aptasensor immobilized on gold nanoparticles/polydopamine hybrid 21 .…”

Section: Introductionmentioning

confidence: 99%

An innovative dual recognition aptasensor for specific detection of Staphylococcus aureus based on Au/Fe3O4 binary hybrid

El-Wekil

Halby

Darweesh

et al. 2022

Sci Rep

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Pathogenic bacteria cause disease outbreaks and threaten human health, prompting the research on advanced detection assays. Herein, we developed a selective molecular imprinted aptasensor for sensitive and prompt quantitation of Staphylococcus aureus (S. aureus) bacteria. The aptasensor was constructed by immobilization of aptamer on gold nanoparticles modified magnetic nanoparticles (apt-AuNPs@ Fe3O4). A functional monomer (o-phenylenediamine, o-phen) was electro-polymerized on the surface of the as-synthesized nanocomposite in the presence of a template (S. aureus). After removing S. aureus, the formed imprinted sites were available to extract pathogenic bacteria from complicated matrices. The surface morphology of the as-fabricated nanocomposites was characterized using different spectroscopic and electrochemical methods. Moreover, we thoroughly evaluated factors affecting the synthesis and determination procedures. The molecular imprinted aptasensor exhibited a wide linear range of 101–107 CFU mL−1 with a Limit of Detection, LOD (signal to noise = 3) of 1 CFU mL−1. The aptasensor detected S. aureus in milk, conduit water, and apple juice samples with good recoveries % and satisfactory relative standard deviations (RSDs %) values.

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Enhanced molecular imprinted electrochemical sensing of histamine based on signal reporting nanohybrid

Cited by 43 publications

References 41 publications

Inspecting Histamine Isolated from Fish through a Highly Selective Molecularly Imprinted Electrochemical Sensor Approach

Inspecting Histamine Isolated from Fish through a Highly Selective Molecularly Imprinted Electrochemical Sensor Approach

In situ engineering of Au–Ag alloy embedded PEDOT nanohybrids at a solvent/non-solvent interface for the electrochemical enzyme-free detection of histamine

An innovative dual recognition aptasensor for specific detection of Staphylococcus aureus based on Au/Fe3O4 binary hybrid

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