Enhanced Natural Strength: Lamiaceae Essential Oils and Nanotechnology in In Vitro and In Vivo Medical Research

Abstract

The Lamiaceae is one of the most important families in the production of essential oils known to have a wide spectrum of biological activity. Recent research has highlighted the dermatological capabilities of various Lamiaceae essential oils, which appear to offer potential in free radical scavenging and anti-inflammatory activity. Some have also been extensively studied for their tissue remodeling and wound-healing, anti-aging, anti-melanogenic, and anti-cancer properties. Certain Lamiaceae essential oils are promising as novel therapeutic alternatives for skin disorders. This potential has seen substantial efforts dedicated to the development of modern formulations based on nanotechnology, enabling the topical application of various Lamiaceae essential oils. This review provides a comprehensive summary of the utilization of various essential oils from the Lamiaceae family over the past decade. It offers an overview of the current state of knowledge concerning the use of these oils as antioxidants, anti-inflammatory agents, wound-healers, anti-aging agents, anti-melanogenic agents, and anticancer agents, both alone and in combination with nanoparticles. Additionally, the review explores their potential applicability in patents regarding skin diseases.

Exploring the Antibacterial Potential of Lamiaceae Plant Extracts: Inhibition of Bacterial Growth, Adhesion, Invasion, and Biofilm Formation and Degradation in Pseudomonas aeruginosa PAO1

“…Previous studies have explored the impact of extracts of Lamiaceae representatives on bacterial growth activity [ 40 , 51 , 52 , 53 , 54 , 55 , 56 , 57 , 58 , 59 ]; however, our literature review revealed that current research mainly focuses on the antibacterial properties of essential oils derived from Lamiaceae plants [ 12 , 50 , 60 , 61 , 62 ]. In our study, B. subtilis showed the highest susceptibility to the effects of Lamiaceae extracts, with H. officinalis and S. officinalis ethanolic and S. scardica methanolic extracts demonstrating the most potent growth-inhibitory activity.…”

D-Limonene: Promising and Sustainable Natural Bioactive Compound

“…Plant essential oils are the main source of aromatic plant odors, which are mainly derived from the roots, stems, leaves, and other organs of plants and have long been used in culinary and medical applications in the historical record [6]. With deeper research, it has been found that plant essential oils have excellent antioxidant activity, antimicrobial activity, and other biological activities [7], which are mainly derived from the constituents of plant essential oils, which are dominated by terpenes and phenyl terpenoids, of which monoterpenoids are the most common [8] and, thus, natural compounds have been incorporated into the study of natural antimicrobial substances. Among the many natural compounds, limonene, due to its widespread presence in the essential oils of various plants, such as Citrus bergamia, Citrus deliciosa, Montanoa quadrangularis, Juniperus oxycedrus, Citrus unshiu, and Bursera graveolens [9,10], and excellent bioactivity has been considered by researchers as a potential sustainable natural active compound [11,12].…”