Enhanced osteogenic differentiation of human mesenchymal stem cells using size-controlled graphene oxide flakes

Park, Sora; Kim, Yun Ki; Kim, Seulha; Son, Boram; Jang, Jyongsik; Park, Tai Hyun

doi:10.1016/j.bioadv.2022.213221

Cited by 2 publications

(1 citation statement)

References 65 publications

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“…Improving the production process of graphene and its derivatives, optimizing the production parameters, or combining it with other materials to promote osteogenesis is the focus of research for a long time in the future. For example, Park enhanced the osteogenic differentiation of BMSCs using size-controlled graphene oxide flakes [ 171 ]. Sun et al used the 3D printing of BMSC-laden highly adhesive artificial periosteum containing gelatin-dopamine and graphene oxide nanosheets to promote bone defect repair [ 172 ].…”

Section: Prospectsmentioning

confidence: 99%

Progress in the application of graphene and its derivatives to osteogenesis

Guo,

Cao,

Wei

et al. 2023

Heliyon

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Section: Prospectsmentioning

confidence: 99%

Progress in the application of graphene and its derivatives to osteogenesis

Guo,

Cao,

Wei

et al. 2023

Heliyon

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Recent Advances in the Design and Structural/Functional Regulations of Biomolecule‐Reinforced Graphene Materials for Bone Tissue Engineering Applications

Li,

Zhao,

Wang

et al. 2024

Small Science

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Biomolecule‐reinforced graphene materials (Bio‐RGMs) have emerged as versatile matrices for biomedical and tissue engineering applications, owing to the combination of graphene‐based materials (GMs) with biomolecular components and their synergistic effects. In this review, an overview of the design, synthesis, structural/functional regulation, and bone engineering applications of various Bio‐RGMs is provided. Both covalent and noncovalent methods for conjugating biomolecules onto GMs, followed by an exploration of the structural diversity of Bio‐RGMs, ranging from 1D nanofibers to 2D membranes and 3D scaffolds/hydrogels/aerogels are discussed. Techniques such as electrospinning, self‐assembly, freeze‐drying, 3D printing, and templated synthesis are highlighted for their roles in designing and fabricating Bio‐RGM architectures. Additionally, specific properties and functions endowed to Bio‐RGMs by biomolecule conjugation, including biocompatibility, cytotoxicity, antibacterial activity, drug delivery ability, and fluorescent sensing are examined. Finally, recent advance is showcased in fabricating Bio‐RGMs for the bone tissue engineering applications of bone repair, regeneration, grafting, drug/cell delivery, and tumor inhibition, and further, the potential of Bio‐RGMs for preclinical applications is analyzed. It is believed that this review will deepen readers’ understanding of biomolecule–GM interactions and inspire the development of innovative Bio‐RGMs for advanced biomedical and tissue engineering applications.

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Enhanced osteogenic differentiation of human mesenchymal stem cells using size-controlled graphene oxide flakes

Cited by 2 publications

References 65 publications

Progress in the application of graphene and its derivatives to osteogenesis

Progress in the application of graphene and its derivatives to osteogenesis

Recent Advances in the Design and Structural/Functional Regulations of Biomolecule‐Reinforced Graphene Materials for Bone Tissue Engineering Applications

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