2024
DOI: 10.1182/blood.2023021944
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Enhanced procoagulant activity of select hemophilia B causing factor IX variants with emicizumab

Kyumin Lee,
Julia Q. Chau,
Yani B. Suber
et al.

Abstract: Emicizumab improves the procoagulant activity of select loss-of-function FIX variants with likely dysfunctional assembly of the intrinsic Xase complex that cause hemophilia B. FVIII-mimetics may represent an alternative non-factor therapy for select hemophilia B patients.

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