Aim
To identify the effect of enhanced recovery after surgery (ERAS) and rapid rehabilitation concepts on the outcomes of patients with haemophilia A undergoing total knee arthroplasty.
Design
Randomized controlled trial.
Methods
The primary endpoint was postoperative hospital stay. The secondary endpoints were pain scores, joint function scores, haemoglobin levels at 3 and 7 days after surgery and satisfaction with hospitalization.
Results
Thirty‐two patients were enrolled. Compared with the routine nursing group, the ERAS group showed shorter postoperative hospital stay (14.2
SD
0.8 vs. 16.6 ± 1.3 days,
p
< .001), smaller amounts of blood transfusion (924
SD
317 vs. 1,263
SD
449 ml,
p
= .020) and coagulation factors (37,325
SD
5,996 vs. 48,475
SD
8,019 U,
p
< .001), lower pain scores at 3 (3.3
SD
0.7 vs. 4.3
SD
0.7,
p
= .002) and 7 (2.3 SD 0.7 vs. 2.8 ± 0.5,
p
= .015) days, lower hospital for special surgery knee scores at 3 (59.9
SD
7.8 vs. 53.6 SD 5.9,
p
= .016) and 7 (77.9
SD
6.9 vs. 71.1 ± 7.1,
p
= .009) days and higher satisfaction with hospitalization (94.3
SD
1.4 vs. 92.7
SD
1.6,
p
= .004).