Enhanced separation of bioactive triterpenic acids with a triacontylsilyl silica gel adsorbent: From impulse and breakthrough experiments to the design of a simulated moving bed unit

Azenha, Ivo S.; Aniceto, José P.S.; Santos, Cristiana Areia dos; Mendes, Adélio; Silva, Carlos M.

doi:10.1016/j.seppur.2020.116991

Cited by 7 publications

(1 citation statement)

References 74 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…SMB is a continuous process technology that can improve the efficiency of adsorbent in the adsorption bed. This SMB technology with multiple columns reduces the solvent and water content consumption, as well as improving the production capacity; it is recognized as the cleanest manufacturing technology in the biomedical industry [1][2][3].…”

Section: Introductionmentioning

confidence: 99%

An Automatic Advanced Fuzzy Controller for Simulated Moving Bed

Xie

Tang

2021

IEEE Access

View full text Add to dashboard Cite

Simulated moving bed (SMB) is one of the most successful technologies in chromatographic separation, which is widely used in chemical industry and food industry. There are many parameters that can affect the separation effect of SMB, and the sensitivity is very strong, so the effective control is always a difficulty problem for SMB. In this paper, a self-tuning advanced fuzzy controller is proposed to control the purity of the SMB outlet, and the study finds it has smaller steady-state error and better adaptability of in SMB when compares with the traditional and advance fuzzy type controller.

show abstract

Section: Introductionmentioning

confidence: 99%

An Automatic Advanced Fuzzy Controller for Simulated Moving Bed

Xie

Tang

2021

IEEE Access

View full text Add to dashboard Cite

show abstract

The Design of Three-Zone Simulated Moving Bed Process for the Separation of Chlorogenic and Gallic Acids Extracted from Spent Coffee Grounds

Nakkong

Tangpromphan

Jaree

2020

Waste Biomass Valor

View full text Add to dashboard Cite

Adsorbents, mobile phases, and strategies for the chromatographic separation of betulinic, oleanolic, and ursolic acids

Azenha

Simões

Mendes

et al. 2023

Biomass Conv. Bioref.

View full text Add to dashboard Cite

A critical overview of the separation of three relevant triterpenic acids, namely betulinic, oleanolic, and ursolic acids, by liquid and supercritical fluid chromatography is presented in this review. These triterpenic acids are commonly found in different biomass residues and have raised great research attention in recent years due to their broad and valuable therapeutic properties. Accordingly, fundamental aspects such as solubilities in single and mixed solvents, commercial stationary phases (octadecylsilyl and other bonded phases like triacontylsilyl, as well as porous graphitic columns), custom adsorbents (molecularly imprinted polymers and other polymeric adsorbents), mobile phases (conventional HPLC solvents and super/subcritical fluids), mobile-phase modifiers (acidic, basic, and cyclodextrins), pre-column derivatization strategies, and influence of temperature have been compiled, analyzed and thoroughly discussed in terms of (calculated) separation selectivities, peaks resolution, orders of elution, systems descriptors, etc. The most relevant achievements and gaps in this area of research are highlighted, together with a final comparison of the separation performance of the chromatographic systems reported in the literature.

show abstract

Enhanced separation of bioactive triterpenic acids with a triacontylsilyl silica gel adsorbent: From impulse and breakthrough experiments to the design of a simulated moving bed unit

Cited by 7 publications

References 74 publications

An Automatic Advanced Fuzzy Controller for Simulated Moving Bed

An Automatic Advanced Fuzzy Controller for Simulated Moving Bed

The Design of Three-Zone Simulated Moving Bed Process for the Separation of Chlorogenic and Gallic Acids Extracted from Spent Coffee Grounds

Adsorbents, mobile phases, and strategies for the chromatographic separation of betulinic, oleanolic, and ursolic acids

Contact Info

Product

Resources

About