Red onion (Allium ascalonicum L.) is one of many horticultural crops consumed by humans as a mixture of spices. For household consumption of about 635 700 tonnes, non-household consumption such as the manufacturing industry amounted to 719 200 tonnes, the sum total of 1.35 million meaning that the deficit for the onion. The purpose of this study was to gain insight about PGPR in increasing the growth and yield of onion, PGPR role in controlling the disease in onions, PGPR concentration in controlling the disease in onions and certain PGPR concentration in the application to control diseases in onion. Using a randomized block design (RAK) factorial 5 x 3 and repeated 3 times. The first factor is the concentration of PGPR with 5 levels ie: p0 (control), P1 (5 ml / liter of water / 2 plants), P2 (10 ml / liter of water / 2 plants), P3 (15 ml / liter of water / 2 plants) and P4 (20 ml / liter of water / 2 plants) and the second factor is the interval provision of PGPR with 3 levels namely: I1 (1 week, 1 x application until the age of 60 days, I2 (2 weeks, 1 x application until the age of 60 day) and I3 (3 weeks, 1 x application until the age of 60 days). the results showed that the onion crop by PGPR could increase plant height (21, 67 cm), number of leaves (32.70 cm), the number of tubers per plant (17.69 g), the wet weight of tuber per plot highs (3460.00 g) and dry weight of tuber per plot (3010.20 g). the provision of PGPR can control fusarium wilt on the red onion. the higher concentration of PGPR with intervals of 3 weeks administration can suppress disease. fusarium wilt PGPR concentration of 20 ml/liter of water with intervals of 3 weeks administration can suppress disease attacks fusarium wilt the lowest (5.22%).