Enhancement of canthaxanthin production from Dietzia natronolimnaea HS-1 in a fed-batch process using trace elements and statistical methods

Nasrabadi, Mohammad Reza Nasri; Razavi, Seyed Hadi

doi:10.1590/s0104-66322010000400003

Cited by 30 publications

(31 citation statements)

References 34 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…It was kept on yeast/malt agar (YMA) plates containing 10 (g/L) glucose, 5 (g/L) yeast extract, 5 (g/L) peptone, 3 (g/L) malt extract and 15 (g/L) agar at pH 7.2. Every month, single colonies were transferred to a fresh plate, incubated for 4 days, and then maintained under refrigeration at 0 to 4 °C (Nasri Nasrabadi and Razavi, 2010a). …”

Section: Methodsmentioning

confidence: 99%

Canthaxanthin biosynthesis by Dietzia natronolimnaea HS-1: effects of inoculation and aeration rate

Rostami¹,

Razavi²,

Sepahi³

et al. 2014

Braz. J. Microbiol.

View full text Add to dashboard Cite

The interest in production of natural colorants by microbial fermentation has been currently increased. The effects of D-glucose concentration (3.18–36.82 g/L), inoculum size (12.5 × 109–49.5 × 109 cfu cells/mL) and air-flow rate (1.95–12.05 L/L min) on the biomass, total carotenoid and canthaxanthin (CTX) accumulation of Dietzia natronolimnaea HS-1 in a batch bioreactor was scrutinized using a response surface methodology-central composite rotatable design (RSM-CCRD). Second-order polynomial models with high R2 values ranging from 0.978 to 0.990 were developed for the studied responses using multiple linear regression analysis. The models showed the maximum cumulative amounts of biomass (7.85 g/L), total carotenoid (5.48 mg/L) and CTX (4.99 mg/L) could be achieved at 23.38 g/L of D-glucose, 31.2 × 109 cfu cells/mL of inoculation intensity and air-flow rate of 7.85 L/L min. The predicted values for optimum conditions were in good agreement with experimental data.

show abstract

Section: Methodsmentioning

confidence: 99%

Canthaxanthin biosynthesis by Dietzia natronolimnaea HS-1: effects of inoculation and aeration rate

Rostami¹,

Razavi²,

Sepahi³

et al. 2014

Braz. J. Microbiol.

View full text Add to dashboard Cite

show abstract

“…This could be due to high availability of reducing sugar present in coconut water. Moreover wide range of micronutrients present in coconut water like TCA cycle intermediates [14,15] may have enhanced the growth of Dietzia maris in this study thus leading to very high pigment yield as influential factors on pigment production is also related with cellular metabolism [5].…”

Section: Production and Supplementation Volume Optimization For Pigmementioning

confidence: 77%

Strong Antioxidant Property of Bacterial Canthaxanthin Obtained by Raw Coconut Water Supplementation as an Additional Nutrient Source

Bera¹,

Sv²,

Chaudhuri³

et al. 2015

March 21-22, 2015 London (UK)

View full text Add to dashboard Cite

“…TCT amount was calculated by using the equation recommended by Nasri Nasrabadi and Razavi (2010a). A Knauer GmbH (Berlin, Germany) HPLC system including a k-1001 HPLC pump, a k-1001 solvent organiser, an on-line degasser, a dynamic mixing chamber, and an UV-Vis detector (K-2600; Knauer GmbH, Berlin, Germany) was used for the determination of individual carotenoids according to the modified method of Razavi et al (2006).…”

Section: Methodsmentioning

confidence: 99%

Enzymatically hydrolysed molasses and sodium citrate as new potentials for the improvement of canthaxanthin batch synthesis by Dietzia natronolimnaea HS-1: A statistical media optimisation

Gharib¹,

Razavi²,

Mousavi³

2014

Czech J. Food Sci.

View full text Add to dashboard Cite

Gharibzahedi S.M.T., Razavi S.H., Mousavi M. (2014): Enzymatically hydrolysed molasses and sodium citrate as new potentials for the improvement of canthaxanthin batch synthesis by Dietzia natronolimnaea HS-1: A statistical media optimisation. Czech J. Food Sci., 32: 326-336.Response surface methodology-central composite rotatable design (RSM-CCRD) was applied to explore the optimum media formulation for maximising canthaxanthin (CTX) biosynthesis by dietzia natronolimnaea HS-1. The effects of three variables of enzymatically hydrolysed molasses (EHM) (16.6-33.4 g/l), sodium (Na)-citrate (21.64-28.36mM), and yeast extract (6.32-9.68 g/l) concentrations on the production of CTX, total carotenoid (TCT), and biomass dry weight (BDW) were appraised. The results showed that the quadratic effects of EHM, yeast extract, and Na-citrate contents in terms of second-order polynomial regression equations (r 2 = 0.968-0.986), respectively, had the most significant effects on the produced TCT and CTX. The predicted maximum accumulation of BDW (8.88 g/l), TCT (7.24 mg/l), and CTX (6.40 mg/l) under the optimum concentrations of the media variables (26.16 g/l EHM, 8.29 g/l yeast extract, and 25.86mM Na-citrate) was very close to the experimental values determined in batch experiments. The high BDW content suggested EHM and Na-citrate as very promising feedstocks for CTX bioproduction by the bacterium studied.

show abstract

Enhancement of canthaxanthin production from Dietzia natronolimnaea HS-1 in a fed-batch process using trace elements and statistical methods

Cited by 30 publications

References 34 publications

Canthaxanthin biosynthesis by Dietzia natronolimnaea HS-1: effects of inoculation and aeration rate

Canthaxanthin biosynthesis by Dietzia natronolimnaea HS-1: effects of inoculation and aeration rate

Strong Antioxidant Property of Bacterial Canthaxanthin Obtained by Raw Coconut Water Supplementation as an Additional Nutrient Source

Enzymatically hydrolysed molasses and sodium citrate as new potentials for the improvement of canthaxanthin batch synthesis by Dietzia natronolimnaea HS-1: A statistical media optimisation

Contact Info

Product

Resources

About