Enhancement of Fluoride Concentration in Saliva after Topical Application of Fluoride Sustained-Release Dosage Form on Orthodontic Plates

Harary, D; Friedman, Michael

doi:10.1002/jps.2600730139

Cited by 9 publications

(2 citation statements)

References 10 publications

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“…Similar results were seen in ado lescents who wore devices for 26 weeks [Kula et al, 1987] and in primates that wore devices for 4 weeks [Shern et al, 1987]. Harary and Friedman [1984] reported the same phenomenon in orthodontic patients who wore ethylcellulose devices.…”

supporting

confidence: 72%

Effect of Artificial Saliva and Calcium on Fluoride Output of Controlled-Release Devices

Adair¹,

Whitford²,

McKnight-Hanes³

1994

Caries Res

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The purpose of this in vitro study was to assess the effect of graded concentrations of calcium in artificial saliva on the output of fluoride from HEMA/ MMA controlled-release devices. After the initial release rates were determined in deionized water, the devices were assigned to five groups. The devices of one group remained in deionized water throughout the 19-day study while those of the other groups were placed in artificial saliva containing 0,4.5, 8.0, or 12.0 mg% calcium on days 4–13. Ten devices of each group were placed in deionized water again on days 14–17 and then in 0.1 mol/l HCl on days 18–19. The five devices of each group that were not placed in deoinized water on day 14 were inspected for surface crystals and then placed in 1 mol/l KOH for 2 days. The fluoride release rates in artificial saliva were reduced by 71–90% and in proportion to the calcium concentration. The release rates in deionized water (days 14–17) approached the baseline values; they exceeded baseline rates by 13–49% while in HCl. The fluoride release rates did not differ among the groups while in KOH, but calcium output was directly related to the calcium concentration of the artificial saliva. The results indicate that fluoride release from HEMA/MMA devices is markedly reduced in artificial saliva and that the reduction is proportional to the concentration of calcium.

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supporting

confidence: 72%

Effect of Artificial Saliva and Calcium on Fluoride Output of Controlled-Release Devices

Adair¹,

Whitford²,

McKnight-Hanes³

1994

Caries Res

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“…Reducing caries by the application of low concentration fluorides over long periods of time has gained attention and initiated work on dental materials and intra-oral release sys tems [Fazzi et al, 1977;Harary and Freidman, 1984;Skartveitetal., 1985;Mirth, 1987;Cooley etal., 1988;HatibovicKofman and Koch, 1991], However, in vivo and in vitro studies have given different results obviously due to the dif ferences in laboratory conditions and oral environment. In dividual differences in salivary flow rate and swallowing frequency may also have affected salivary fluoride concen trations [Jenkins, 1978].…”

Section: Discussionmentioning

confidence: 99%

Salivary and Urinary Fluoride Levels after 1-Month Use of Fluoride-Releasing Removable Appliances

Alaçam

Ulusu²,

Bodur³

et al. 1996

Caries Res

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Forty children aged 8–10 years participated in this study. Half (n = 20) of them used orthodontic appliances which contained fluoride-releasing devices embedded in the lingual surface of the appliance and the other half used orthodontic appliances prepared from a fluoride-releasing acrylic polymer. Prior to the adjustment of appliances and after 1, 7, 14, 21 and 30 days salivary and urinary samples were collected and the fluoride concentrations were determined. The mean fluoride release was highest during the first week. However, the values decreased considerably after that and the curves for the two groups became parallel. The results indicate that fluoride-releasing removable appliances could be useful for a prolonged release of low concentrations of fluoride without any systemic effect.

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Slow-release fluoride devices for the control of dental decay

Bonner¹,

Clarkson

2005

Cochrane Database of Systematic Reviews

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Background Slow-release fluoride devices have been investigated as a potentially cost-effective method of reducing dental caries in people with high risk of disease. This is the second update of the Cochrane Review first published in 2006 and previously updated in 2014. Objectives To evaluate the effectiveness and safety of different types of slow-release fluoride devices on preventing, arresting, or reversing the progression of carious lesions on all surface types of primary (deciduous) and permanent teeth.

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Enhancement of Fluoride Concentration in Saliva after Topical Application of Fluoride Sustained-Release Dosage Form on Orthodontic Plates

Cited by 9 publications

References 10 publications

Effect of Artificial Saliva and Calcium on Fluoride Output of Controlled-Release Devices

Effect of Artificial Saliva and Calcium on Fluoride Output of Controlled-Release Devices

Salivary and Urinary Fluoride Levels after 1-Month Use of Fluoride-Releasing Removable Appliances

Slow-release fluoride devices for the control of dental decay

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