Abstract:Low-level laser irradiation (LLLI) stimulates bone regeneration and may be useful for bone fracture and oral implant therapy. However, the molecular mechanism of LLLI in accelerating bone formation is not well known. In order to understand the mechanism of LLLI in accelerating bone formation, we attempted to identify gene expressions enhanced by LLLI by a subtractive gene cloning and DNA microarray analysis. Osteoblastic cell MC3T3-E1 was treated with 830 nm Ga-Al-As diode laser irradiation and total mRNA was … Show more
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