Enhancement of mixing and reaction efficiency of various fluids applications at different microfluidic configuration and design

Wong, Whui Dhong; Majnis, Mohd Fadhil; Lai, Chin Wei; Sagadevan, Suresh; Muhd Julkapli, Nurhidayatullaili

doi:10.1016/j.cep.2024.109729

Chemical Engineering and Processing - Process Intensification

2024

DOI: 10.1016/j.cep.2024.109729

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Enhancement of mixing and reaction efficiency of various fluids applications at different microfluidic configuration and design

Whui Dhong Wong,

Mohd Fadhil Majnis,

Chin Wei Lai

et al.

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2024

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Cited by 4 publications

References 137 publications

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Experimental assessment of bulk vs microfluidic reactors for nano-bio-photocatalyst synthesis and antibiotic degradation

Sohrabi,

Moraveji

2024

Int. J. Environ. Sci. Technol.

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Experimental assessment of bulk vs microfluidic reactors for nano-bio-photocatalyst synthesis and antibiotic degradation

Sohrabi,

Moraveji

2024

Int. J. Environ. Sci. Technol.

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Recent advances in continuous flow synthesis of metal–organic frameworks and their composites

Senthil Raja,

Tsai

2024

Chem. Commun.

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Zweifach–Fung Microfluidic Device for Efficient Microparticle Separation: Cost-Effective Fabrication Using CO2 Laser-Ablated PMMA

Rodríguez,

Báez-Suárez,

Muñoz-Camargo

et al. 2024

Micromachines

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Microfluidic separators play a pivotal role in the biomedical and chemical industries by enabling precise fluid manipulations. Traditional fabrication of these devices typically requires costly cleanroom facilities, which limits their broader application. This study introduces a novel microfluidic device that leverages the passive Zweifach–Fung principle to overcome these financial barriers. Through Lagrangian computational simulations, we optimized an eleven-channel Zweifach–Fung configuration that achieved a perfect 100% recall rate for particles following a specified normal distribution. Experimental evaluations determined 2 mL/h as the optimal total flow rate (TFR), under which the device showcased exceptional performance enhancements in precision and recall for micrometer-sized particles, achieving an overall accuracy of 94% ± 3%. Fabricated using a cost-effective, non-cleanroom method, this approach represents a significant shift from conventional practices, dramatically reducing production costs while maintaining high operational efficacy. The cost of each chip is less than USD 0.90 cents and the manufacturing process takes only 15 min. The development of this device not only makes microfluidic technology more accessible but also sets a new standard for future advancements in the field.

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Enhancement of mixing and reaction efficiency of various fluids applications at different microfluidic configuration and design

Cited by 4 publications

References 137 publications

Experimental assessment of bulk vs microfluidic reactors for nano-bio-photocatalyst synthesis and antibiotic degradation

Experimental assessment of bulk vs microfluidic reactors for nano-bio-photocatalyst synthesis and antibiotic degradation

Recent advances in continuous flow synthesis of metal–organic frameworks and their composites

Zweifach–Fung Microfluidic Device for Efficient Microparticle Separation: Cost-Effective Fabrication Using CO2 Laser-Ablated PMMA

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