Scientific knowledge is growing rapidly,
particularly in biochemistry,
an interdisciplinary subject in which the courses attract diverse
students with varied disciplinary interests and career goals. Thus,
there is a need to teach skills and concepts in biochemistry in a
way that is both compelling to a variety of learners and also relevant
to careers in science, health, and related areas. This article describes
a pair of literature-based group writing assignments developed for
a two-semester biochemistry sequence with 30–50 students per
section. Adaptable to application in many biochemistry courses, these
projects reinforce core threshold concepts while teaching information
literacy skills and connecting to biochemistry applications in medicine
and technology. Strategies for structured instruction and management
prior to and during work on the assignments are presented for instructors
in order to maximize student success and impact. While writing assignments
have become commonplace in upper-division biology courses, such a
matched pair of mini-review assignments for a two-semester biochemistry
sequence interweaving information literacy, core concepts, and applications
has not been reported previously. Improved performance from the first
to second semester indicates that these assignments help students
learn skills that are useful for self-directed learning.