Enhancement of Release and Solubility of Curcumin from Electrospun PEO–EC–PVP Tripolymer-Based Nanofibers: A Study on the Effect of Hydrogenated Castor Oil
Abstract:This study reveals
the state-of-the-art fabrication of a tripolymer-based
electrospun nanofiber (NF) system to enhance the release, solubility,
and transdermal penetration of curcumin (Cur) with the aid of in situ
release of infused castor oil (Co). In this regard, Cur-loaded Co-infused
polyethylene oxide (PEO), ethyl cellulose (EC), and polyvinyl pyrrolidone
(PVP) tripolymer-based NF systems were developed to produce a hybridized
transdermal skin patch. Weight percentages of 1–4% Cur and
3–10% of Co were blen… Show more
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