Enhancement of the biocompatibility by surface nitriding of a low‐modulus titanium alloy for dental implant applications

Abstract

To enhance their longevity dental implants must be highly biocompatible and must have a low elastic modulus close to that of the bone. They must also possess a high superficial hardness and a high corrosion resistance. For these reasons a recently developed low modulus Ti-27Nb alloy with non-toxic elements was treated by gas nitriding at high temperature in this study. A very thin nitrided layer of 0.5µm in thickness followed by an enriched nitrogen zone was observed. Consequently, a very high hardness evaluated at about 1800 HV was obtained in surface, which represents an increase of 4-5 times the hardness of the non nitrided alloy. This superficial hardness was experimentally observed to decrease up to 800 nm in depth from the surface to the core. The low modulus of Ti-27Nb (evaluated at 55 GPa, which is twice lower than the commercially pure titanium) was not affected by the surface nitriding treatment. A better corrosion resistance was observed as well as a significant decrease in ion release rates for the nitrided alloy (ion release of 1.41 ng/cm 2 compared to the 163.58 ng/cm 2 obtained for the commercially pure titanium at pH=7.48 in artificial Carter-Brugirard saliva). The cytocompatibility was not compromised and the cell viability performed on human osteoblasts, fibroblastic cells and epithelial cells was enhanced on the nitrided surface in comparison with the non-nitrided surface. These combined properties make the nitrided Ti-27Nb alloy a good candidate for dental implant applications.

Antibacterial and Antioxidant Effects of Magnesium Alloy on Titanium Dental Implants

“…So, once oral cavity is damaged, it is easy to be complicated with bacterial infection. Ti alloy is the most widely used metal implant in dental implant repair, which can provide a stable base for the later crown restoration [ 19 ]. However, after implant placement, bacteria in the oral cavity will invade through the gap between the implant and the periodontal tissue, causing inflammation and osseointegration instability, eventually resulting in the occurrence of implant failure [ 20 ].…”

Hybrid cardiovascular sourced extracellular matrix scaffolds as possible platforms for vascular tissue engineering

“…Statistical analysis was performed using one‐way analysis of variance (ANOVA) with post hoc Fisher test for DNA content, CellTiter‐Blue®, and real‐time qPCR, unless stated otherwise. One‐way ANOVA with post hoc Fisher's test has been widely used in literature when comparing a large range of variable sizes (Bédouin, Gordin, Pellen‐Mussi, et al, ; Nayak & Brenner, ; Vogels et al, ; Woods & Gratzer, ).…”

Enhanced corrosion resistance of zinc-containing nanowires-modified titanium surface under exposure to oxidizing microenvironment

“…Titanium (Ti) and its alloys have been widely used in bone tissue engineering applications for decades because of their satisfactory biocompatibilities and excellent mechanical properties, especially for dental applications [1–3]. Among all of these properties, a rapid, strong and long-life bond between implant and bone is essential and fundamental [4].…”