Enhancing anti-angiogenic immunotherapy for melanoma through injectable metal–organic framework hydrogel co-delivery of combretastatin A4 and poly(I:C)

Xiao, Xufeng; Zheng, Yunuo; Wang, Tianlong; Zhang, Xiaoqing; Fang, Gaochuan; Zhang, Zhonghai; Zhang, Zhengkui; Zhao, Jiaojiao

doi:10.1039/d4na00079j

Nanoscale Adv.

2024

DOI: 10.1039/d4na00079j

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Enhancing anti-angiogenic immunotherapy for melanoma through injectable metal–organic framework hydrogel co-delivery of combretastatin A4 and poly(I:C)

Xufeng Xiao,

Yunuo Zheng,

Tianlong Wang

et al.

Abstract: The combination approach utilizing a ZIF-8/HA injectable hydrogel to co-deliver CA4 and PIC can enhance therapeutic effects by inhibiting tumor vascularization and boosting macrophage-mediated anti-tumor responses.

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2025

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A novel life for antitumor combretastatins: Recent developments of hybrids, prodrugs, combination therapies, and antibody-drug conjugates

Fantacuzzi,

Carradori,

Giampietro

et al. 2025

European Journal of Medicinal Chemistry

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A novel life for antitumor combretastatins: Recent developments of hybrids, prodrugs, combination therapies, and antibody-drug conjugates

Fantacuzzi,

Carradori,

Giampietro

et al. 2025

European Journal of Medicinal Chemistry

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Enhancing anti-angiogenic immunotherapy for melanoma through injectable metal–organic framework hydrogel co-delivery of combretastatin A4 and poly(I:C)

Abstract: The combination approach utilizing a ZIF-8/HA injectable hydrogel to co-deliver CA4 and PIC can enhance therapeutic effects by inhibiting tumor vascularization and boosting macrophage-mediated anti-tumor responses.

Cited by 1 publication

References 38 publications

A novel life for antitumor combretastatins: Recent developments of hybrids, prodrugs, combination therapies, and antibody-drug conjugates

A novel life for antitumor combretastatins: Recent developments of hybrids, prodrugs, combination therapies, and antibody-drug conjugates

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