Enhancing polysaccharide production by Paraisaria dubia spores batch fermentation through a pH-shift strategy based on kinetic analysis

Li, Yuan; Tong, Lingling; Wang, Yue; Du, Yuan‐Hang; Liu, Mengzhen; He, Shao‐Jie; Wei, Shi‐Xiang; Zhang, Yidan; Chen, Zilei; Jin, Suxing; Guo, Dong‐Sheng

doi:10.1016/j.procbio.2022.12.020

Cited by 4 publications

(2 citation statements)

References 35 publications

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“…This approach not only accelerated cell growth but also effectively curbed the accumulation of by‐products 23 . Yuan proposed a pH‐shift strategy based on the analysis of fermentation kinetics parameters, leading to a significant 47.6% improvement in polysaccharide production by Paraisaria dubia 24 …”

Section: Resultsmentioning

confidence: 99%

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Enhancing Bacillus licheniformis sporulation with automatic nitrogen feeding based on online detection of exhaust CO₂

Ding,

Wang,

Jiang

et al. 2023

AIChE Journal

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The Bacillus licheniformis formulation is effective in environmental remediation, gut microbiota modulation, and soil improvement. Adequate spore quantity is crucial for activity of B. licheniformis formulations. This study aimed to enhance B. licheniformis BF‐002 sporulation by optimizing nitrogen source feeding. In the initial four manual feeding strategies, continuous feeding based on exhaust CO2 resulted in the highest cell and spore quantities (1.44 × 1010 and 6.12 × 109 cfu/mL). Python‐based automatic feeding, based on online exhaust CO2 detection, was developed and implemented in 5 and 50 L cultivations. Compared to manual feeding, cell and spore quantities increased by 31.25% and 97.7%, respectively. Substituting costly peptone (fish) with NH4Cl reduced spore quantity by 8.46% and 9.25% in 5 and 50 L cultivations, while cutting nitrogen source cost by 87.08% and 91.39%. Employing exhaust CO2 concentration for automatic nitrogen supplementation effectively promotes Bacillus growth and spore formation.

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Section: Resultsmentioning

confidence: 99%

“…23 Yuan proposed a pH-shift strategy based on the analysis of fermentation kinetics parameters, leading to a significant 47.6% improvement in polysaccharide production by Paraisaria dubia. 24 (A) (B)…”

Section: Automatic Feeding Based On Feedback From Exhaust Gas Co 2 Co...mentioning

confidence: 99%

Enhancing Bacillus licheniformis sporulation with automatic nitrogen feeding based on online detection of exhaust CO₂

Ding,

Wang,

Jiang

et al. 2023

AIChE Journal

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Development of a green fermentation strategy with resource cycle for the docosahexaenoic acid production by Schizochytrium sp.

Chen

Yang

et al. 2023

Bioresource Technology

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Preparation and characterization of novel antioxidant peptides from protein hydrolysate of Ophiocordyceps gracilis

Zhang,

Lian,

Yang

et al. 2024

Process Biochemistry

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Enhancing polysaccharide production by Paraisaria dubia spores batch fermentation through a pH-shift strategy based on kinetic analysis

Cited by 4 publications

References 35 publications

Enhancing Bacillus licheniformis sporulation with automatic nitrogen feeding based on online detection of exhaust CO₂

Enhancing Bacillus licheniformis sporulation with automatic nitrogen feeding based on online detection of exhaust CO₂

Development of a green fermentation strategy with resource cycle for the docosahexaenoic acid production by Schizochytrium sp.

Preparation and characterization of novel antioxidant peptides from protein hydrolysate of Ophiocordyceps gracilis

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Enhancing polysaccharide production by Paraisaria dubia spores batch fermentation through a pH-shift strategy based on kinetic analysis

Cited by 4 publications

References 35 publications

Enhancing Bacillus licheniformis sporulation with automatic nitrogen feeding based on online detection of exhaust CO2

Enhancing Bacillus licheniformis sporulation with automatic nitrogen feeding based on online detection of exhaust CO2

Development of a green fermentation strategy with resource cycle for the docosahexaenoic acid production by Schizochytrium sp.

Preparation and characterization of novel antioxidant peptides from protein hydrolysate of Ophiocordyceps gracilis

Contact Info

Product

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Enhancing Bacillus licheniformis sporulation with automatic nitrogen feeding based on online detection of exhaust CO₂

Enhancing Bacillus licheniformis sporulation with automatic nitrogen feeding based on online detection of exhaust CO₂