Doping, or in more morally neutral terms, enhancement, has always been present in sport practice and not only at the present time, which is marked by professionalism and competitiveness. The latest development in doping seems linked to biotechnological advances, and one of the techniques that will apparently be particularly important in the near future is neuroscience, notably through pharmacological enhancers and transcranial stimulators. These devices promise to improve not only physiological aspects in sport performance, but also mental and emotional ones. On the other hand, they can seriously affect sport ethics insofar as they can be economically accessible to professional and amateur athletes. This chapter explores these issues.