External wall thermal insulation is one of the most effective solutions on the market to increase energy efficiency in the built environment. Off-Site Construction (OSC), through better control of the various parameters involved, can bring important advantages, such as the reduction of construction time, the improvement of product and process quality, etc. In the last years, the rapidly growing demand for thermal insulation systems, stimulated also by tax incentives, has generated a unique situation in Italy compared to the rest of Europe, also leading to a considerable fragmentation of the supply chain with several players involved (component and system manufacturers, distributors, and installers). The complexity of such context makes Italy an extremely challenging and insightful case study for a supply chain and sustainability study, also considering the fact that the energy efficiency of the Italian building stock represents a crucial challenge to achieve the country's energy saving goals since 40% of final energy consumption derives from buildings and 75% of the building stock presents a low energy performance (energy labels E, F and G). This article presents both an analysis of the Italian market of manufacturers of building envelope thermal insulation solutions, highlighting the different players in the supply chain in terms of number, type, and marketed products and solutions, and a focus on sustainable and recycled materials. The study also aims to define a methodology to investigate the state of play and opportunities for industrialisation of this market and its bottlenecks. In the article, a questionnaire is proposed to collect information and opinions on the spread of OSC and the perception of companies and professionals regarding the advantages and disadvantages of industrializing the sector. A first validation of the survey is presented in the form of industrial focus groups.