Enhancing the colorimetric detection of H₂O₂and ascorbic acid on polypyrrole coated fluconazole-functionalized POMOFs

Abstract

For the first time, a bifunctional colorimetric biosensing platform has been developed, based on a polypyrrole coated fluconazole-functionalized polyoxometalate-based metal–organic framework with ultrahigh stability for the enhanced detection of H2O2 and ascorbic acid.

Biocompatible Platinum Nanoclusters Prepared Using Bitter Gourd Polysaccharide for Colorimetric Detection of Ascorbic Acid

“…Therefore, the concentration of ascorbic acid was positively correlated with the change of absorbance of oxTMB. Figure 7 a showed that the relationship between the absorbance of mixed solution at 652 nm and the concentration of ascorbic acid (2–100 μM) was linear, and this upper limit was a relatively high concentration in the existing literature [ 24 ]. The linear regression equation was ΔA = 1.823C AA + 0.0906 (R 2 = 0.993), and the detection limit was 0.191 μM.…”

Programmable starving-photodynamic synergistic cancer therapy

“…Here, we also discussed the effects of H 2 O 2 under light irradiation on the generation of •OH in solution using 3,3ʹ,5,5ʹ-tetramethylbenzidine (TMB) as the indicator. TMB can be oxidized to a blue product with a characteristic absorption peak at 652 nm by •OH [38]. As shown in Fig.…”

Polyoxometalate‐Based Metal Organic Frameworks: Recent Advances and Challenges

“…So researchers have managed to combine it with MOF which also exhibited peroxidase‐responsive activity to synthesize a novel colorimetric biosensor [51,52] . In early studies, a series of simple, low‐cost, and highly sensitive colorimetric assays were derived for the detection of H 2 O 2 [53,54] . In recent years, it has been tried to be combined with other materials, thus creating many POMOFs‐based platforms for the detection of different biological materials, [55,56] Li et al.…”

“…[51,52] In early studies, a series of simple, low-cost, and highly sensitive colorimetric assays were derived for the detection of H 2 O 2 . [53,54] In recent years, it has been tried to be combined with other materials, thus creating many POMOFs-based platforms for the detection of different biological materials, [55,56] Li et al synthesized a POMOF/SWNT composite to develop a simple, fast-response and highly feasible "switch" for the detection of L -Cys colorimetric platform, which has the lowest detection limit (0.103 μM) for Lcysteine ( L -Cys) among all types of sensors to date. (Figure 7) [57] They synthesized the POMOF/SWNT composite nanoplatform using a simple ultrasound-driven periodic functionalization strategy, and PXRD patterns and IR spectra showed that its peak did not change after simulated peroxidase activity, and it maintained high enzymatic activity after 5 cycles of experiments, reflecting its good stability.…”