“…A new research framework entitled ‘Symptomics’ was proposed recently that aims to describe such studies under one framework, and complement diagnosis-level research with more detailed research on symptoms (Fried, 2017). Symptomics has three cornerstones:- The relationship of individual symptoms with important variables such as risk factors, biomarkers, impairment of functioning, and treatment response (Bentall et al, 2012; Costello, 1993; Fried & Nesse, 2015b; Hieronymus, Emilsson, Nilsson, & Eriksson, 2016; Persons, 1986);
- The analysis of the potentially causal relations among symptoms in symptom networks (Borsboom, 2017; Cramer, Waldorp, van der Maas, & Borsboom, 2010; Wichers, Wigman, & Myin-Germeys, 2015);
- Gaining better understanding of psychopathology by investigating personalized processes at the level of individuals instead of heterogeneous groups of patients (Fisher & Boswell, 2016; Molenaar, 2004).
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